Leukocyte Alkaline Phosphatase/ LAP, LAP Smear Indications :
A cytochemical reaction is useful in differential diagnosis of myeloproliferative disease, distinguishing leukemoid reaction from leukemia. Helps in the differential diagnosis of chronic granulocytic leukemia versuys leukemoid reaction, aid in the evaluation of polycythemia and myelobrois.
Normal Range :
counts of 11 to 95
Low scores have been associated with CML, PNH, thrombocytopenic purpura, and hereditary phpophosphatasia. In CML regardless of the total white count, the score remains low. Test Method :
Enzyme reaction with leukocyte alkaline phosphatase liberating naphthol – Spectrophotometer assay.Related Tests :
Leukocyte cytochemistry, White Blood Count