Antibiotic to kill the bacteria that cause tuberculosis could be developed based on the binding properties of fidaxomicin (Fdx). Fidaxomicin (Fdx) acts like a doorstop to jam the enzyme in an open state, preventing the motions necessary to secure promoter DNA in the active site.
Heart valve disease is caused when one or more valves of the heart are damaged, which affects the blood flow. TAVR- transcatheter aortic valve replacement is a minimally invasive surgery that repairs a damaged heart valve. Patients who undergo this surgery have experienced a significant increase in their quality of life,
Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique that uses strong magnetic fields and radio waves to look into structures inside the human body. A large international multi-center study has shown that performing an MRI scan as the first step in suspected prostate cancer patients can cut down the need for prostate biopsies in a quarter of the men.
Sepsis is defined as life-threatening organ dysfunction due to an impaired host response to infection, and is still a leading cause of death in acutely ill patients. New microfluidic device developed by scientists at the Massachusetts General Hospital (MGH) accurately measures migration patterns of neutrophils (a type of white blood cell important in the immune response).