Calcium Surplus in Brain Cells may Cause Parkinson's Disease
Excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease, research at the University of Cambridge finds. The international team found that calcium can mediate the interaction between small membranous structures inside nerve endings, which are important for neuronal signaling in the brain, and alpha-synuclein, the protein associated with Parkinson's disease.