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Drug information on Duplat (Cisplatin) from Samarth Pharma Pvt. Ltd.

Duplat   Injection Samarth Pharma Pvt. Ltd. Generic : Cisplatin	82.00 10ml 1

Information Checked by Dhanalakshmi Chinnuswamy, Diploma in Pharmacy, MBA (Healthcare)

Further Checked by The Medindia Medical Review Team on February, 2, 2017

Medindia currently has information on 3080 generic drugs and 110,061 brands that have their prices listed. New drugs with their prices are listed as and when they get approved by the drug controller. Please do write to us (info@medindia.net) if a drug is missing from our comprehensive drug price list.

Bladder Cancer

Bone Marrow Transplantation

Cancer- Oropharyngeal Cancer of the Head and Neck

Cervical Cancer

Gallbladder Cancer

Gastric Cancer

Laryngeal Cancer

Lung Cancer

•   Toxic effects : Nephrotoxicity (kidney damage) and ototoxicity (ear damage).

•   Severe effects : Stroke, heart attack, electrolyte disturbances and allergic reactions.

•   Gastrointestinal : Loss of appetite, nausea and vomiting.

•   ENT : Ringing in the ear, loss of hearing and deafness.

Adult: IV- Metastatic ovarian cancer As monotherapy: 100 mg/m² per cycle, given as a single dose once every 4 week.
For combination therapy with cyclophosphamide: 75-100 mg/m² on day 1 of every 4-week cycle. Metastatic testicular tumors 20 mg/m²/day for 5 days per cycle. Advanced bladder cancer 50-70 mg/m² per cycle once every 3-4 week.

It comes as a solution for injection to be administered by a healthcare provider into the vein.

Contraindicated in patients with hearing impairment, kidney impairment and hypersensitivity.

• Caution should be exercised in patients with history of bone marrow suppression, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast-feeding.

• Monitor complete blood counts, ear and neurological functions regularly while taking this medication.

• Patients may develop with increased risk of nephrotoxicity (kidney damage with irritation), drink adequate fluids to prevent damage.

• Avoid vaccination while taking this medication.

• It may develop new type of cancer; if you have any doubt consult with your doctor regarding this.

Avoid excess dosage.

This drug is used only under the supervision of physician.