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Cisplatin is a platinum-based chemotherapy agent, prescribed for ovarian cancer, bladder cancer and metastatic testicular tumors either alone or with other medications.  It stops cancer cell growth.

Drug information on Cisplatin (Cisplatin) from Khandelwal Laboratories Pvt. Ltd.


Khandelwal Laboratories Pvt. Ltd.
Generic : Cisplatin
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Medical Condition(s) for which Cisplatin may be prescribed

Side effects of Cisplatin

   Toxic effects : Nephrotoxicity (kidney damage) and ototoxicity (ear damage).

   Severe effects : Stroke, heart attack, electrolyte disturbances and allergic reactions.

   Gastrointestinal : Loss of appetite, nausea and vomiting.

   ENT : Ringing in the ear, loss of hearing and deafness.

Dosage & When it is to be taken (Indications)

Adult: IV- Metastatic ovarian cancer As monotherapy: 100 mg/m2 per cycle, given as a single dose once every 4 week.
For combination therapy with cyclophosphamide: 75-100 mg/m2 on day 1 of every 4-week cycle. Metastatic testicular tumors 20 mg/m2/day for 5 days per cycle. Advanced bladder cancer 50-70 mg/m2 per cycle once every 3-4 week.

How to use Cisplatin?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

When is Cisplatin not to be taken? (Contraindications)

Contraindicated in patients with hearing impairment, kidney impairment and hypersensitivity.

Warnings and Precautions for Cisplatin

Caution should be exercised in patients with history of bone marrow suppression, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast-feeding.

• Monitor complete blood counts, ear and neurological functions regularly while taking this medication.

• Patients may develop with increased risk of nephrotoxicity (kidney damage with irritation), drink adequate fluids to prevent damage.

• Avoid vaccination while taking this medication.

• It may develop new type of cancer; if you have any doubt consult with your doctor regarding this.

Other Precautions for Cisplatin

Avoid excess dosage.

Storage Conditions for Cisplatin

This drug is used only under the supervision of physician.

Schedule : G  Drugs that are to be used only under medical supervision.

Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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Substitutes for Cisplatin

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