New mRNA Injection for Heart Attack Recovery

A new mRNA injection aims to treat heart attack patients by promoting blood vessel growth and improving heart muscle recovery using relaxin hormone.

An Injection, renowned for its COVID-19 vaccine, has now turned its attention to heart health with an innovative mRNA treatment. This new injection, known as mRNA-0184, aims to help patients recover from heart attacks and heart failure. This new approach uses messenger RNA (mRNA) focused on healing the heart().

The Goal: Rebuilding the Heart

Heart attacks often lead to cell death in the heart muscle, making it difficult for the heart to pump blood efficiently. One of the main goals of the mRNA-0184 injection is to stimulate revascularization, or the growth of new blood vessels. These new vessels help restore blood flow, which is vital for healing the heart.

Personalized mRNA Vaccine and Immunotherapy Combination Reduces Risk of Melanoma Recurrence
Combining mRNA vaccination with immunotherapy reduces melanoma recurrence or mortality by 44% compared to immunotherapy alone.

‘The injection uses messenger RNA (mRNA) to instruct heart cells to produce #relaxin, a hormone that promotes blood vessel growth and improves blood flow. #hearthealth #medindia ’

The drug is currently undergoing a Phase 1B clinical trial to test its safety and determine optimal dosage. Patients with stable heart failure have begun receiving the injection. This trial will assess how well the patients tolerate the shot and how effective it is in improving heart function over time.

How the mRNA Injection Works and Role of Relaxin in Heart Health

The shot is designed to be injected directly into the heart of patients who have suffered a heart attack or are dealing with heart failure. Using the same mRNA technology that powered the COVID vaccine, this injection directs heart cells to produce relaxin, a hormone known to improve blood flow.

This is crucial for patients whose heart muscle has been damaged and can’t regenerate on its own. This hormone has the potential to make a big difference for people who have suffered heart damage.

Why Do mRNA Vaccines Cause Side Effects?
Scientists in Australia have found why mRNA vaccines trigger side effects, paving the way for more effective vaccines.

Heart attacks often result in lasting damage, with many patients readmitted due to complications. This innovative approach could pave the way for a new era in heart disease recovery, using science to potentially “heal” the heart at a molecular level. If successful, it could revolutionize treatments for heart failure and improve recovery after heart attacks.

Reference:

Moderna begins trialing mRNA shot that is injected directly into the HEART to treat heart attack patients - (https://www.dailymail.co.uk/health/article-11627695/Moderna-begins-trialing-mRNA-shot-injected-directly-HEART.html)

Pure mRNA Synthesis Revolutionizes Vaccine Production
Learn how the chemical synthesis method for mRNA can accelerate vaccine production, enhancing responses to viral outbreaks and advancing future medical treatments.

Source-Medindia

Does Young Adults' Risk of Heart Attacks Rise After COVID-19?
Recent ICMR Study reveals that the alarming trend of myocardial infarctions in seemingly healthy individuals has not been limited to COVID-19 alone.