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Drug information on Zoladex (Goserelin) from AstraZeneca Pharma India Ltd.


AstraZeneca Pharma India Ltd.
Generic : Goserelin

Drug Name : Goserelin

Goserelin(Zoladex Inj) generic Zoladex is a synthetic analogue of gonadotropin-releasing hormone (GnRH) agonist, used to suppress production of the hormones (testosterone and estrogen), prescribed for the treatment of endometriosis, breast and prostate cancer.
More Info about Goserelin

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Zoladex may be prescribed

Side effects of Zoladex

  Genitourinary: Vaginal bleeding and dryness, increase in menstrual bleeding, hot flushes, sexual dysfunction and breast swelling/tenderness.

  Central Nervous System: Headache, emotional lability, depression, sleeplessness, dizziness and tingling.


Joint pain, sweating and injection site reactions.

Dosage & When it is to be taken (Indications)

Palliative treatment of prostate cancer: Adult- 3.6 mg injected into the anterior abdominal wall every 28 days or 10.8 mg every 12 weeks. An anti-androgen is given several days before beginning of the treatment and continued for at least 3 weeks to prevent disease flare.

How to use Zoladex?

Implant placed by your doctor or nurse in a hospital.

When is Zoladex not to be taken? (Contraindications)

Contraindicated in women who are or may become pregnant and breastfeeding; patients with known hypersensitivity.

Warnings and Precautions for Zoladex

It may cause urinary tract obstruction, spinal cord compression, and decreases bone density in women.

• Women should take contraceptives.

•Monitor blood sugar regularly, it may affect blood sugar.

• Monitor men at tumor risk.

• Caution should be exercised in patients with history of urinary problems, spinal cord problems, mental illness, diabetes, heart problems, blood vessel problems, stroke, high blood calcium levels, obesity, any allergy, and who are taking other medications.

Other Precautions for Zoladex

Monitor bone mineral density regularly.

Storage Conditions for Zoladex

Injection: Store below 25°C.Store it at room temperature and keep away from children.

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For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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