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Flupirtine - Indications, Dosage, Side Effects and Precautions

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Information about Flupirtine

Generic Name : Flupirtine
Up-to-date prescription details regarding Flupirtine are provided here.

Pronunciation : Flu-pir-tine

Learn the correct pronunciation of the Flupirtine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Therapeutic Classification : Analgesics

Trade Names/Brand Names of Flupirtine

India :

Overview of Flupirtine

• Flupirtine is nonopioid, non-NSAID analgesic.
• It is used for the treatment of acute and chronic pain including migraine, post-traumatic pain, post-surgical pain and injuries.

Why is Flupirtine Prescribed? (Indications)

Flupirtine is a non-opioid, non-NSAID painkiller (analgesic).
It is used for the treatment of acute and chronic pain like post-traumatic pain, post-surgical pain, headache and menstrual cramps.
It acts through a different mechanism as compared to opioid and non-steroidal anti-inflammatory (NSAID) painkillers.

When should Flupirtine not be taken? (Contraindications)

Flupirtine should not be used in the following conditions:

• Allergy to the drug
• Liver disease including hepatic encephalopathy, cholestasis, primary biliary cirrhosis
• Myasthenia gravis
• Chronic alcoholism
• Pregnancy and breastfeeding
• Children below 6 years of age

What is the dosage of Flupirtine?

• The usual recommended dose in adults is 300 to 400 mg /day.

How should Flupirtine be taken?

• Flupirtine should be taken in three divided dose orally.
• Rectal suppositories are also available which are administered into the rectum.

What are the warnings and precautions for Flupirtine?

• Dose reduction is required in individuals with kidney disease.

What are the side effects of Flupirtine?

Nervous system: Dizziness, drowsiness, mood changes, ataxia (lack of muscle coordination during voluntary activities), restlessness, nervousness
Skin: Itching
Digestive tract: Nausea, vomiting, dry mouth, stomach fullness, heartburn
Others: Muscle tremors, liver dysfunction

What are the other precautions for Flupirtine?

• Do not take the rectal suppositories orally.

What are the Drug Interactions of Flupirtine?

• Flupirtine may increase the effect of oral anticoagulants like warfarin.
• Flupirtine may increase the adverse effects of drugs like paracetamol, alcohol and sedatives
• Avoid use with the anti-epileptic drug carbamazepine.

What are the storage conditions for Flupirtine?

• Flupirtine should be stored in a cool and dry place.
• Keep it away from heat.
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