Last Updated on Jul 29, 2014


Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or its inputs and/or outputs are affected. The causes are mostly related to our nervous system.

Ataxia is a condition where a person lacks coordination during voluntary movement. He walks with an unstable gait and loses balance. His trunk may sway from side-to-side. He may show symptoms like slurring of speech, involuntary eye movements, difficulty with swallowing and tremor with movement. MRI scans helps in its diagnosis and the treatment of the conditions depends on its cause.


Anatomy and Physiology

The cerebellum is a part of the brain that is located in the lower back portion of the skull. It helps a person to maintain balance and posture. It is also the centre for coordinating voluntary movements. It receives signals from sense organs that include inner ear, eye, muscle, joints and skin. These signals travel through the spinal cord to the cerebellum. The cerebellum also receives inputs and sends output to other parts of the brain such as brainstem, thalamus, vestibular nuclei and cortex.

Any condition that affects the cerebellum or signals going to and from the cerebellum causes ataxia.

  • When the cerebellum is mainly affected, the ataxia is called cerebellar ataxia.
  • If the cerebellum is unaffected but is unable to receive signals, the ataxia is called sensory ataxia.

In sensory ataxia, the spinal cord, thalamus, cortex or nerves may be affected. It can be differentiated from cerebellar ataxia through a test called Rhomberg test. In this test, the patient is asked to stand with feet together and eyes open. He is then asked to close his eyes. If the patient starts swaying once his eyes are closed, the test is said to be positive. This test indicates that signals from the joints are not conveyed to the brain when the eyes are closed and is positive in sensory ataxia. In pure cerebellar ataxia, the person may not be able to stand erect without swaying even with eyes open.

In vestibular ataxia, the signals from the inner ear are unable to reach the brainstem and cerebellum. A patient with vestibular ataxia often experiences vertigo i.e. a feeling that either the patient or his surroundings are spinning. In addition, he may exhibit involuntary movement of the eyes and loss of balance. Some common causes include inflammation of the inner ear or vestibular nerve that carries signals, trauma, lack of blood supply and some drugs that affect the inner ear.

Ataxia is usually diagnosed with MRI and genetic studies are done in cases of hereditary ataxias. They do not have any specific treatment. Some cases may recover spontaneously whereas others may undergo further complications.


  1. Harrison’s Principles of Internal Medicine 17th edition
  2. Brunberg JA. Ataxia. American Journal of Neuroradiology 2008; 29:1420-1422

Latest Publications and Research on Ataxia


kenny66 Thursday, July 19, 2018


Willowkitty Wednesday, August 6, 2014

I cannot walk a straight line. It was so bad Sunday that I went to the hospital to see if I had a stroke. No stroke, no MS, taking meds for heart attack back in December. Doctors don't know what is causing it. Very frustrated.

Imayavaramban Saturday, June 21, 2014

Last month, I got injured in my head due to road accident. I found some symptoms in me relevant to ataxia. What should i do next ?

Jimbo1789 Monday, December 3, 2012

I got ataxia from interferon shots. Collapsed one day, wound up in hospital for 2 weeks in a coma, had pneumonia, anemia requiring transfusion, dysphagia, dyskinesia and dysarthria, After 3 months of therapy speech is still affected and still cannot walk w/o qualified supervision. Are there any treatments available?

marnie65 Friday, July 20, 2012

For the last two months, I have had Bacteremia four times with E-Coli ESBL, and Proteus. I have been covered extensively with Gentamicin and Vancomycin. My Creatinine has been rising and is now 131. My GFR has been decreasing, which is now 38. As well, I have lost my sense of balance and I am experiencing a great deal of difficulty walking. Initially I thought this was due to severe anemia, HGB 88, with iron depletion. Now I wonder about ataxia from the aminoglycocides, and if this is the case, is it reversible?

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