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Last Updated : 11/22/2017

General Information on Ethionamide

Generic Name : Ethionamide

Pronunciation : ETH-eye-ON-a-mide

Latest prescription information about Ethionamide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.1 | Therapeutic Classification : Anti- Tuberculosis

Trade Names/Brand Names of Ethionamide

Overview of Ethionamide

Ethionamide is an antibiotic which is used for the treatment of tuberculosis.

Why is Ethionamide Prescribed? (Indications)

Ethionamide is an antibiotic. It is used for the treatment of tuberculosis as a second-line drug in combination with other drugs, especially in cases of resistance to the standard drugs. 

When should Ethionamide not to be taken? (Contraindications)

It is contraindicated in patients allergic to drugs or with severe liver impairment.
It should not be used in porphyria.

What is the dosage of Ethionamide?

The recommended adult dose for ethionamide is 5 to 20 mg/kg tablet.
Start with a low dose and increase over every one to two days to a maximum dose of 1 g/day.

How should Ethionamide be taken?

Ethionamide should be taken once daily or in divided doses after the meal as directed by the physician.

What are the warnings and precautions for Ethionamide?

Caution should be taken in patients with diabetes mellitus or kidney disease
Liver function tests and eye examinations should be conducted on a regular basis during treatment
Caution should be taken in patients with thyroid dysfunction.

What are the side effects of Ethionamide?

  Digestive system: Nausea, vomiting, diarrhea, abdominal pain, stomatitis, loss of appetite
  Nervous System: Drowsiness, dizziness, restlessness, psychiatric disturbances, peripheral neuropathy, headache and seizure
  Eye: Blurring of vision, double vision, optic neuropathy
  Liver: Hepatitis, jaundice
  Cardiovascular: Low blood pressure
  Others: Skin reactions, impotence, reduced white blood cell and platelet counts, allergic reactions, joint pain

What are the other precautions for Ethionamide?

Do not use the drug during pregnancy.
It is important to complete the course of the tuberculosis medicines even if the patient is feeling well.

What are the Drug Interactions of Ethionamide?

Alcohol may enhance the adverse effect of ethionamide resulting in a psychotic episode.
Ethionamide should not be taken in combination with cholera or other live vaccines as the antibiotic may diminish the therapeutic effects of the vaccines.
Ethionamide may increase the side effect of cycloserine.
Ethionamide may increase the blood level of isoniazid.

What are the storage conditions for Ethionamide?

It should be stored Store at 20C to 25C.

Last Updated : 11/22/2017
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