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Ethionamide is an antibiotic. It is used for the treatment of tuberculosis as a second-line drug in combination with other drugs, especially in cases of resistance to the standard drugs. 

Drug information on Ethide (250mg) (Ethionamide) from Lupin Laboratories Ltd.

Ethide (250mg)

  Film coated tablet
Lupin Laboratories Ltd.
Generic : Ethionamide
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Medical Condition(s) for which Ethide (250mg) may be prescribed

Overview of Ethide (250mg)

• Ethionamide is an antibiotic which is used for the treatment of tuberculosis.

Side effects of Ethide (250mg)

  Digestive system: Nausea, vomiting, diarrhea, abdominal pain, stomatitis, loss of appetite

  Nervous System: Drowsiness, dizziness, restlessness, psychiatric disturbances, peripheral neuropathy, headache and seizure

  Eye: Blurring of vision, double vision, optic neuropathy

  Liver: Hepatitis, jaundice

  Cardiovascular: Low blood pressure

  Others: Skin reactions, impotence, reduced white blood cell and platelet counts, allergic reactions, joint pain

Dosage & When it is to be taken (Indications)

• The recommended adult dose for ethionamide is 5 to 20 mg/kg tablet.
• Start with a low dose and increase over every one to two days to a maximum dose of 1 g/day.

How to use Ethide (250mg)?

• Ethionamide should be taken once daily or in divided doses after the meal as directed by the physician.

When is Ethide (250mg) not to be taken? (Contraindications)

• It is contraindicated in patients allergic to drugs or with severe liver impairment.
• It should not be used in porphyria.

Warnings and Precautions for Ethide (250mg)

• Caution should be taken in patients with diabetes mellitus or kidney disease
• Liver function tests and eye examinations should be conducted on a regular basis during treatment
• Caution should be taken in patients with thyroid dysfunction.

Other Precautions for Ethide (250mg)

• Do not use the drug during pregnancy.
• It is important to complete the course of the tuberculosis medicines even if the patient is feeling well.

Drug Interactions of Ethide (250mg)

• Alcohol may enhance the adverse effect of ethionamide resulting in a psychotic episode.
• Ethionamide should not be taken in combination with cholera or other live vaccines as the antibiotic may diminish the therapeutic effects of the vaccines.
• Ethionamide may increase the side effect of cycloserine.
• Ethionamide may increase the blood level of isoniazid.

Storage Conditions for Ethide (250mg)

• It should be stored Store at 20°C to 25°C.

Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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