Reduced insulin sensitivity is associated with smaller brain size and impaired language skills in elderly, reveals study published in Diabetes Care.
The main hormonal function of insulin is to support the uptake and use of glucose in muscles and fat tissues. However, in an earlier article recently published in Molecular Neurobiology, Christian Benedict from the Department of Neuroscience at Uppsala University has reported that when insulin reaches the brain, it enhances memory function in humans. As insulin's capacity to stimulate glucose metabolism generally declines with age, it may also be that it affects the rate of cognitive aging in seniors.
In a new study, Christian Benedict, together with colleagues from Uppsala University (Samantha Brooks, Håkan Ahlström, Lars Lind, and Helgi Schiöth), the UK, and the US, have systematically studied 331 men and women at the age of 75 years. The researchers examined whether insulin sensitivity is tied to brain health. The brain structure of each participant was measured using magnetic imaging technology, so-called MRT, and their language skills were tested by asking them to name as many animals as possible in one minute (so-called verbal fluency).