About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Statin Drugs Reduce Mortality Risk by 33% in Arthritis Patients

Font : A-A+

Highlights:
  • Ankylosing spondylitis and Psoriatic arthritis are forms of arthritis that affects the spinal cord, skin and joints respectively.
  • Statin drugs are used to lower the lipids and reduce inflammation in ankylosing spondylitis and psoriatic arthritis patients.
  • Initiating statin drugs in ankylosing spondylitis and psoriatic arthritis were found to lower mortality rate by 33%.

Statin Drugs Reduce Mortality Risk by 33% in Arthritis Patients

Use of Statins by patients with ankylosing spondylitis or psoriatic arthritis were found to have a low mortality risk by 33%, finds a study from Massachusetts General Hospital, Boston.

The research findings was presented at the American College of Rheumatology Annual Scientific Meeting in Washington this week.

Advertisement


Statin drugs are usually prescribed to lower the lipids and reduce inflammation in patients with ankylosing spondylitis and psoriatic arthritis patients.

Ankylosing spondylitis is a form of arthritis which affects the spine and causes inflammation of the spinal joints. It is more likely to affect men with HLA antigen and who lack rheumatoid factor.
Advertisement

Psoriatic arthritis is form of arthritis which usually occurs after psoriasis and may damage the joints. Psoriasis is a chronic skin condition which results in red patches of the skin.

A research team from the Massachusetts General Hospital, Boston has recently found the benefits of statins in reducing the mortality rate of patients with ankylosing spondylitis or psoriatic arhritis.

Amar Oza, MD, a rheumatologist at Massachusetts General Hospital along with his team said, "The expanding literature on the dual-role of statins to lower both inflammation and cholesterol levels has naturally led to interest in the role of statins in inflammatory arthritis."

"A randomized trial found such a dual benefit among patients with rheumatoid arthritis (RA), and a population-based study of patients with RA found a survival benefit associated with statin use as well. As such, we hoped to quantify the potential impact of statins in the seronegative spondyloarthropathies, as the risk of all-cause mortality and even cardiovascular-specific mortality has shown to be elevated in these conditions."

The research study was conducted on the population database of patients with ankylosing spondylitis or psoriatic arthritis between 2001 to 2014. Fifty different variables including disease duration, socioeconomic status, body-mass index, lifestyle articles and medication use were studied.

Out of 2904 patients with ankylosing spondylitis or psoriatic arthritis who started statins, 271 patients died during a follow up with a mean of 5.3 years. And in patients who did not take statins 376 people died during a follow up in a mean of 5.15 years.

Dr. Oza said, "Given the increased risk of mortality and cardiovascular disease compared to the general population, patients with seronegative spondyloarthropathies like Ankylosing Spondylitis and Psoriatic Arthritis may benefit from the dual anti-inflammatory and lipid-lowering properties of statins, perhaps even more than in the general population."

"This observational study raises the possibility that clinicians may have a lower threshold for starting their patients on statins to mitigate this mortality risk. To that effect, it sets the groundwork for potential clinical trials to come, which will provide high-level evidence about the impact statins have on their health."

The author concludes that further research is required to study the potential benefits of statin therapy to reduce mortality and other cardiovascular causes.



Source: Medindia

Citations   close

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Madhumathi Palaniappan. (2016, November 14). Statin Drugs Reduce Mortality Risk by 33% in Arthritis Patients. Medindia. Retrieved on Aug 08, 2022 from https://www.medindia.net/news/healthwatch/statin-drugs-reduce-mortality-risk-by-33-in-arthritis-patients-165224-1.htm.

  • MLA

    Madhumathi Palaniappan. "Statin Drugs Reduce Mortality Risk by 33% in Arthritis Patients". Medindia. Aug 08, 2022. <https://www.medindia.net/news/healthwatch/statin-drugs-reduce-mortality-risk-by-33-in-arthritis-patients-165224-1.htm>.

  • Chicago

    Madhumathi Palaniappan. "Statin Drugs Reduce Mortality Risk by 33% in Arthritis Patients". Medindia. https://www.medindia.net/news/healthwatch/statin-drugs-reduce-mortality-risk-by-33-in-arthritis-patients-165224-1.htm. (accessed Aug 08, 2022).

  • Harvard

    Madhumathi Palaniappan. 2021. Statin Drugs Reduce Mortality Risk by 33% in Arthritis Patients. Medindia, viewed Aug 08, 2022, https://www.medindia.net/news/healthwatch/statin-drugs-reduce-mortality-risk-by-33-in-arthritis-patients-165224-1.htm.

Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test Your Knowledge on Lung Transplantation
Baldness can be Cured and Prevented: let us see How!
Drinking Beer or Wine Every Day Could Cause Age-related Diseases
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cholesterol Drug Toxicity Osteoarthritis Oligoarthritis Spondylolisthesis Knee Replacement Cholesterol - The Enigma Chemical Reactive Arthritis Statins Drugs Banned in India 

Most Popular on Medindia

Loram (2 mg) (Lorazepam) Vent Forte (Theophylline) Calculate Ideal Weight for Infants Post-Nasal Drip Turmeric Powder - Health Benefits, Uses & Side Effects Color Blindness Calculator Iron Intake Calculator Nutam (400mg) (Piracetam) Accident and Trauma Care A-Z Drug Brands in India
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use