About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Gut Hormone Benefits Obese Patients

by Sheela Philomena on January 12, 2012 at 1:19 PM
Font : A-A+

 Gut Hormone Benefits Obese Patients

Gut hormone helps overweight or obese patients lose weight, reveals study.

Glucagon-like peptide-1 (GLP-1) is a hormone that is secreted from the intestine when we eat.

Advertisement

GLP-1 based therapy was recently introduced as a new treatment for patients with type 2 diabetes because of its ability to regulate blood sugar levels.

But it also suppresses food intake and appetite, making it an interesting approach in the treatment of obesity.

So researchers at the University of Copenhagen set out to determine the effect of glucagon-like peptide-1 receptor (GLP-1R) agonists on weight loss. They also looked at their effect on blood pressure, cholesterol and liver enzyme levels, and blood sugar (glycaemic) control.
Advertisement

They analysed the results of 25 randomised controlled trials involving over 6,000 patients. Differences in study design and quality were taken into account to minimise bias.

They found that patients who received clinically relevant doses of GLP-1R agonists for at least 20 weeks achieved a greater weight loss compared with the control groups.

The benefit was seen for patients with and without type 2 diabetes, but may be more pronounced in patients without diabetes.

GLP-1R agonists also had beneficial effects on blood pressure, cholesterol and improved glycaemic control in patients with type 2 diabetes. There was no statistically significant effect on liver enzymes.

Common side effects included nausea, vomiting and diarrhoea, but did not seem to affect the number of patients dropping out of the trials, suggesting that overall patient satisfaction with the treatment is relatively high.

The finding has been published on bmj.com.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Get Involved and Stand Up for Human Rights on Human Rights Day 2022
Coronary Artery Bypass Grafting
Macronutrients Calculator for Weight Loss
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Battle of the Bulge Probiotics - Support System for the Gut Leaky Gut Syndrome 

Most Popular on Medindia

Sinopril (2mg) (Lacidipine) Diaphragmatic Hernia Iron Intake Calculator Drug - Food Interactions Drug Side Effects Calculator Accident and Trauma Care Drug Interaction Checker Pregnancy Confirmation Calculator Loram (2 mg) (Lorazepam) Color Blindness Calculator
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Gut Hormone Benefits Obese Patients Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests