Autophagy: Self-Repair Mechanism at Cellular Level - Latest News and Research Updates

Health News Posted on January 22, 2021 -

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Biochemical Pathway That Protects Cells from Cell Death Identified

A newly identified biochemical pathway protects cells from a type of cell death called ferroptosis, said Moffitt Cancer Center researchers. The findings of the study are published in Cell Metabolism. The hallmarks of cancer include rapid cell ...

Anti-diarrhea Drug Loperamide Triggers Cell Death In Glioblastoma Cells

In glioblastoma cell lines, anti-diarrhea drug loperamide helps induce cell death, revealed a research group led by Dr Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University. Scientists have now ...

Kidney Damage in Diabetes Linked to Autophagy

Highlights: Autophagy in diabetes initially increases and then reduces due to the activation of a pathway Tumor suppressor gene p53 activates miRNA miR-214 and inhibits autophagy gene ULK1 Inhibition of autophagy gene results in ...

Scientists Identify Early Beta Cell Death in Type 1 Diabetes

Scientists have discovered beta cell death in children and adults with recent-onset type 1 diabetes and in antibody-positive at-risk subjects before disease onset. The study was conducted by Anath Shalev, M.D., and colleagues at the University of ...

Drug-induced Cellular Membrane Complexes to Cause Cancer Cell Death

Cell membrane complexes named ceramidosomes could be a new target for drugs to kill cancer cells, discovered by the researchers at Hollings Cancer Center at the Medical University of South Carolina (MUSC). This discovery began while figuring ...

Mild Stress, Dream Sleep are Associated with Pathways of Brain Cell Death and Survival

Stress and rapid-eye-movement (REM) sleep are linked to pathways of brain cell death and survival, reports a new study. The findings of the study are published in the PNAS journal . The first and most distinct consequence of daily mild ...

Autophagy Turns Out To Be Bad For Cancer: Study

Autophagy, a cellular recycling process which was previously thought to be bad has been found to be good. In the study, scientists actually found it to be assisting in stopping the growth of cancer. The results of this study are published in the ...

Novel Chemical May Help Prevent Inflammatory Cell Death

New study discovers a way to end the death of immune cells which is linked to multiple diseases, including inflammatory bowel disease (IBD), sepsis, and arthritis. The findings of the study are published in the journal Science Immunology . ...

Enzyme That Causes Cell Death in Multiple Sclerosis Identified

Cell death that affects most vulnerable cells in multiple sclerosis (MS) is linked to the enzyme ‘gasdermin’ (GSDMD) , according to a research team at the University of Alberta Faculty of Medicine & Dentistry. After identifying the process ...

Heart Failure and Cardiac Cell Death can be Brought to a Stop

Inhibition of OMA1 which activates heart stress could be targeted for the prevention of heart failure finds a new study. The findings of this study are published in the Science Translational Medicine . The new target, a mitochondrial protease ...

Natural Cell Death - Risk for Diabetes and Heart Diseases

Highlights: Death receptors in the blood may serve as markers for development of diabetes and heart diseases. Increased cell death is seen in type 2 diabetes and arteriosclerosis. Individuals with high plasma levels of death receptors ...

Discovery of New Cell Death Mechanism may Delay Degenerative Disorders

Understanding new cell death mechanism involved in debilitating neuro-degenerative disorders may help delay these disorders found a new study published in Current Biology journal. This novel research, published today in Current Biology, ...

Forest Fire Causes DNA Damage and Lung Cell Death

Pollutants from forest fire not only induce inflammation, oxidative stress, and cause genetic damage in human lung cells, but they also drove one-third of the cultured cells to death. This has been found by a research team who worked with particles ...

Advancement of Tissue Injury could be Prevented by Limiting Cell Death

Highlights New insights into the cell death process could help prevent asthma exacerbation and tissue damage in brain or kidney injury Ferroptosis, the highly regulated cell death programme can be uncontrolled in traumatic brain and ...

Chronic Cell Death Promotes Liver Cancer

Liver cancer occurs predominantly in patients whose liver has been damaged as a result of chronic disease. Until now it has remained in the dark how these events are linked at molecular level. An international team of scientists from the German ...

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