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Drug information on Grastim (Filgrastim) from Dr. Reddy's Laboratories Ltd.


Dr. Reddy's Laboratories Ltd.
Generic : Filgrastim

Drug Name : Filgrastim

Filgrastim(Neupogen) generic Grastim stimulates the production of white blood cells. It is prescribed for neutropenia. It is also used to decrease the incidence of infection in cancer patients who are under chemotherapy treatment or a bone marrow transplant. It may be given to cancer patients prior to chemotherapy, following which the white blood cells are collected. These are then given back into the patient after chemotherapy so that the white blood cell count comes back to normal.
More Info about Filgrastim

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Medical Condition(s) for which Grastim may be prescribed

Side effects of Grastim

  Most Common: Mild to moderate bone and muscle pain and allergic reaction.

  Central Nervous System: Dizziness, fatigue and headache.

  Skin: Rash, hair loss, inflammation of blood vessels in the skin, Sweet's syndrome, redness or swelling at the site of injection.

  Gastrointestinal: Nausea, vomiting, mouth ulcer, constipation, loss of appetite, sore throat and diarrhea.

  Respiratory: Shortness of breath, trouble breathing and wheezing.

  ENT: Nosebleed.

♦ •  Musculoskeletal: Decreased bone density.

  Potentially Fatal: Pulmonary infiltrates leading to respiratory failure or acute respiratory distress syndrome and rupture of the spleen.

Dosage & When it is to be taken (Indications)

Adult: SC/IV: The recommended dose is 5 to 10 mcg/kg/day for 4-7 days.

How to use Grastim?

It comes as a solution for injection, administered by a healthcare provider into the vein or under the skin.

When is Grastim not to be taken? (Contraindications)


Warnings and Precautions for Grastim

Caution should be exercised in patients with history of blood cancer, sickle-cell disease; bone disease, withdraw treatment if there are signs of pulmonary infiltrate, fluid retention or heart failure, pregnancy and breastfeeding.

• Monitor complete blood count, bone density in patients with osteoporosis (long-term treatment).

• Regular examination of structure and functions of bone-marrow cells should be done in severe congenital neutropenia.

Other Precautions for Grastim

Do not stop this medication without your healthcare provider's advice.

Storage Conditions for Grastim

Injection: Refrigerate at 2-8°C. Do not freeze. Keep this medication in an airtight container, and out of reach of children.

♦ Safety Labeling Changes Approved By FDA

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For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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