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Drug information on Grafeel PFS (300mcg/mL) (Filgrastim) from Dr. Reddy's Laboratories

Grafeel PFS (300mcg/mL)

Dr. Reddy's Laboratories
Generic : Filgrastim
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Medical Condition(s) for which Grafeel PFS (300mcg/mL) may be prescribed

Side effects of Grafeel PFS (300mcg/mL)

  Most Common: Mild to moderate bone and muscle pain and allergic reaction.

  Central Nervous System: Dizziness, fatigue and headache.

  Skin: Rash, hair loss, inflammation of blood vessels in the skin, Sweet's syndrome, redness or swelling at the site of injection.

  Gastrointestinal: Nausea, vomiting, mouth ulcer, constipation, loss of appetite, sore throat and diarrhea.

  Respiratory: Shortness of breath, trouble breathing and wheezing.

  ENT: Nosebleed.

♦ •  Musculoskeletal: Decreased bone density.

  Potentially Fatal: Pulmonary infiltrates leading to respiratory failure or acute respiratory distress syndrome and rupture of the spleen.

Dosage & When it is to be taken (Indications)

Adult: SC/IV: The recommended dose is 5 to 10 mcg/kg/day for 4-7 days.

How to use Grafeel PFS (300mcg/mL)?

It comes as a solution for injection, administered by a healthcare provider into the vein or under the skin.

When is Grafeel PFS (300mcg/mL) not to be taken? (Contraindications)


Warnings and Precautions for Grafeel PFS (300mcg/mL)

Caution should be exercised in patients with history of blood cancer, sickle-cell disease; bone disease, withdraw treatment if there are signs of pulmonary infiltrate, fluid retention or heart failure, pregnancy and breastfeeding.

• Monitor complete blood count, bone density in patients with osteoporosis (long-term treatment).

• Regular examination of structure and functions of bone-marrow cells should be done in severe congenital neutropenia.

Other Precautions for Grafeel PFS (300mcg/mL)

Do not stop this medication without your healthcare provider's advice.

Storage Conditions for Grafeel PFS (300mcg/mL)

Injection: Refrigerate at 2-8°C. Do not freeze. Keep this medication in an airtight container, and out of reach of children.

♦ Safety Labeling Changes Approved By FDA

Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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