Tacrolimus - Indications, Dosage, Side Effects and Precautions


Information about Tacrolimus

Generic Name : Tacrolimus
Up-to-date prescription details regarding Tacrolimus are provided here.

Pronunciation : tak-roe-li-mus

Learn the correct pronunciation of the Tacrolimus, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y43.4 Therapeutic Classification : Immunosuppressants

Trade Names/Brand Names of Tacrolimus

India :

International :

Prograf, Protopic

Why is Tacrolimus Prescribed? (Indications)

This medication is an immunosuppressant, prescribed for preventing organ rejection during transplantation. It decreases the activity of immune system to prevent an organ from rejection.

When should Tacrolimus not be taken? (Contraindications)


What is the dosage of Tacrolimus?

Topical- As 0.03% ointment- Apply a thin layer over the affected skin twice daily.

How should Tacrolimus be taken?

It comes as an ointment to apply topically as directed by your physician.

What are the warnings and precautions for Tacrolimus?

• Caution should be exercised in patients with heart, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• Patient may develop with increased risk of skin cancer; avoid exposure to sunlight.

• Wear protective clothing and sunscreen with a high skin protection factor (SPF) to avoid sunburn.

• Wear sunglasses avoid eye damage.

• It may increase blood pressure; monitor blood pressure level regularly while taking this medication.

• Patient may experience with the following symptoms: thirst, excessive hunger, frequent urination, blurred vision and confusion.

• Avoid vaccination while taking this medication.

What are the side effects of Tacrolimus?

Gastrointestinal - Loss of appetite, constipation, dehydration, gastrointestinal disorder, rectal disorder, hernia, intestinal inflammation, mouth ulcer and infection.
Central Nervous System - Anxiety, dizziness, increased muscle tone, abnormal thinking, uneasiness and headache.
Heart - Vein inflammation, heart disease, dilatation of blood vessels, fainting, fast heart rate and chest pain.
Skin - Photosensitivity reaction, skin cancer, skin discoloration, skin overgrowth, skin ulcer, white patches on the skin and sweating.
Eye and ENT - Abnormal vision, eye swelling, taste perversion, tooth decay, dry eyes, ear disorder, nosebleed and eye pain.
Respiratory - Difficulty in breathing, lung disorder and inflammation of larynx.
Metabolic - Increased cholesterol level and over active thyroid.
Musculoskeletal - Joint inflammation, tendon disorder, nail disorder, neck pain and joint disorder.
Genitourinary - Unintended pregnancy and vaginal infection/inflammation.
Miscellaneous - Chills, fungal infection and swelling in the extremities.

What are the other precautions for Tacrolimus?

Avoid excess dosage.

What are the storage conditions for Tacrolimus?

Store it at room temperature (25°C).
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