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Pimozide - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Pimozide

Generic Name : Pimozide
Pronunciation : pi’ moe zide
Latest prescription information about Pimozide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.5 | Therapeutic Classification : Psychotherapeutics
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Trade Names/Brand Names of Pimozide

India : 

International : 

Orap
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Why is Pimozide Prescribed? (Indications)

This medication is a tranquilizer, prescribed for tourette syndrome and resistant tics. It blocks the action of dopamine.
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When should Pimozide not be taken? (Contraindications)

Contraindicated in patients with simple tics, who are taking pemoline, methylphenidate, amphetamines, celexa or lexapro, CNS depression and hypersensitivity.

What is the dosage of Pimozide?

Child- Dose of 0.05 mg/kg once at bedtime. The dose may be increased every third day to a maximum of 0.2 mg/kg not to exceed 10 mg/day.
Adult- 0.2 mg/kg per day, or 10 mg/day. Doses greater than 0.2 mg/kg/day or 10 mg/day are not recommended.

How should Pimozide be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Pimozide?

• Caution should be exercised in patients with history of seizures, an abnormal electroencephalogram (EEG), neuroleptic malignant syndrome (NMS), alcohol abuse, or depression, irregular heart beat, heart, liver or kidney disease, enlarged prostate, increased eye pressure, low blood pressure, decrease in white blood cells, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

What are the side effects of Pimozide?

   Body as a Whole : Headache.
   Gastrointestinal : Dry mouth, diarrhea, nausea, vomiting, constipation, belching, increased thirsty and appetite.
   Endocrine : Menstrual disorder and breast secretions.
   Musculoskeletal : Muscle cramps and muscle tightness.
   Central Nervous System : Drowsiness, sedation, sleeplessness, dizziness, weakness, rigidity, speech disorder, handwriting change, depression, excitement and nervousness.
   Eye : Visual disturbances, taste change, sensitivity to light and black spots.
   Genitourinary : Impotence.

What are the other precautions for Pimozide?

Avoid excess dosage.

What are the storage conditions for Pimozide?

Store it at room temperature and in an airtight container.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Learn more about Pimozide's interaction with Food, Herbs and Alcohol



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