- Antipyrine-Benzocaine Otic - (https://medlineplus.gov/druginfo/meds/a607073.html )
- Efficacy of phenazone in the treatment of acute migraine attacks: a double-blind, placebo-controlled, randomized study - (https://pubmed.ncbi.nlm.nih.gov/15377321/)
- Therapeutic properties and tolerance of procaine and phenazone containing ear drops in infants and very young children - (https://pubmed.ncbi.nlm.nih.gov/19998578/)
- Ear drops for the removal of ear wax - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492540/)
Information about Phenazone
Generic Name : PhenazoneUp-to-date prescription details regarding Phenazone are provided here.
Pronunciation : Phe-Na-zone
Learn the correct pronunciation of the Phenazone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
Therapeutic Classification : Analgesic And Antipyretic Agent
Trade Names/Brand Names of Phenazone
India :
Other Name(s) of Phenazone
AntipyrineOverview of Phenazone
• Phenazone, also called antipyrine, is used orally for fever and painful conditions like migraine and as ear drops to treat ear ache.Why is Phenazone Prescribed? (Indications)
Phenazone, also called antipyrine, is usedOrally to reduce fever and pain in conditions like migraine.
As ear drops, as a pain reliever and a local anesthetic:
For the treatment of ear ache caused by an acute inflammation of the middle ear (acute otitis media) in a combination with other medications
Along with benzocaine before ear wax removal to facilitate the removal of the earwax, and after the removal to dry the external ear canal and relieve any discomfort
When should Phenazone not be taken? (Contraindications)
Phenazone is contraindicated in the following conditions:• Allergy to the drug
• Glucose-6-phosphate dehydrogenase deficiency
• Acute hepatic porphyria
• Pregnancy and during breastfeeding
• Children
• The ear drops should not be used in patients with a perforated ear drum or discharge from the ear
What is the dosage of Phenazone?
• The recommended dose of phenazone is:Oral: 1 g every 4 to 8 hourly; maximum of 4 g in a day
As ear drops: 3 to 4 drops into the external ear canal. It should be administered three times daily for 2 to 3 days to soften the ear wax. It can be used every 1-2 hourly for the treatment of earache as needed.
How should Phenazone be taken?
• The external ear canal can be covered with a cotton plug moistened with the ear drops solution after putting the drops if the doctor advises the same.What are the warnings and precautions for Phenazone?
• If you do not feel better in two to three days with the medication, contact your doctor• Stop using the drug if you develop an allergic reaction. Phenazone should be used with caution in individuals allergic to other drugs or substances
• Do not use phenazone in patients with blood count abnormalities
• Caution should be taken in patients with upcoming surgery
• Avoid touching the tip of the dropper to the ears, fingers or anywhere else to prevent contamination
What are the side effects of Phenazone?
Ear: Burning, redness, swelling, and pain in the ear, dizzinessOthers: Allergic reactions that may include skin rash, itching, swelling of face, breakdown of red blood cells (hemolysis), porphyria
What are the other precautions for Phenazone?
• Do not use the drug if you are allergic to it• Inform your doctor if you are pregnant or breastfeeding, or planning a pregnancy before using the medication
What are the Drug Interactions of Phenazone?
• The oral drug may reduce the effect of warfarin• Medications like phenytoin, carbamazepine, barbiturates, spironolactone and rifampin may reduce the effect of phenazone
• Medications like cimetidine, disulfiram, propranolol, verapamil, diltiazem, amiodarone, oral contraceptives and ketoconazole may increase the blood level of phenazone
What are the storage conditions for Phenazone?
• Keep out of reach of children.• Store at room temperature.
• Discard the ear drops a few months after opening as advised by the manufacturer. Replace the cap of the dropper after use.
