Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Paroxetine

Generic Name : Paroxetine

Pronunciation : pa rox' e teen

Latest prescription information about Paroxetine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.2 | Therapeutic Classification : Psychotherapeutics

Why is Paroxetine Prescribed? (Indications)

This medication is an SSRI antidepressant, prescribed for major depression, obsessive-compulsive disorder, panic disorder, social anxiety and generalized anxiety disorder. It increases the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

When should Paroxetine not to be taken? (Contraindications)

Contraindicated in patients who are taking monoamine oxidase inhibitors (MAOIs), pimozide, and hypersensitivity.

What is the dosage of Paroxetine?

PO- The recommended initial dose is 20 mg/day.

How should Paroxetine be taken?

It comes as a tablet and liquid to take by mouth, with or without food.

What are the warnings and precautions for Paroxetine?

Caution should be exercised in patients with history of increased eye pressure, seizures, stomach bleeding, liver, kidney or heart disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

Patient may develop with increased risk of Neuroleptic malignant syndrome (NMS) and Serotonin Syndrome with the following symptoms: fever, rigid muscles, blood pressure changes, mental changes, restlessness, diarrhea, fast heart beat, incoordination, nausea, vomiting. If it is so consult with your doctor.

What are the side effects of Paroxetine?

   Most Common : Weakness, sweating, nausea, decreased appetite, drowsiness, dizziness, sleeplessness, tremor, nervousness, ejaculatory disturbance, and other male genital disorders.
   Body as a Whole : Headache.
   Heart : Palpitations and dilatation of blood vessels.
   Skin : Sweating and rash.
   Gastrointestinal : Nausea, dry mouth, constipation, diarrhea, decreased appetite, flatulence and indigestion.
   Musculoskeletal : Muscle pain and weakness.
   Central Nervous System : Anxiety, tingling, decreased sexual activity and confusion.
   Eye and ENT : Respiration problems, blurred vision and taste perversion.
   Genitourinary : Ejaculatory disturbances, urinary frequency, urination disorder and female genital disorders.

What are the other precautions for Paroxetine?

Avoid excess dosage.

What are the storage conditions for Paroxetine?

Store it at room temperature, away from direct sunlight and excess heat and moisture.

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sapphirenilam, Mauritius

Hi Washim, I am 23 from Mauritius too and I am about to start treatment with Pari LP. I think i need to talk to you, can you please contact me?

1dansimmons, Canada

Why is Dr.Herar prescropting me zanax or paxcil and telling me he is giving me a muscle relaxant?. Is he doing something wrong?!.

depgenmed, India

can i take pari cr 12.5 bd and lamitor 25 h.s at the same time how long to come out from depression.my email add depgenmed@rediffmail.com.

ravindra6349, India

i am taking paradise XR 25 FOR 4 year.What to do I have. How can long take this. RAVINDRA SINGH

Washim, Mauritius

I'm 25 years, male from Mauritius and I'm taking Pari LP twice a day since 1 month and I'm having a problem. I'm not ejaculating while masturbing or having sexual intercourse. Is it the medicine please?

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