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Metoprolol - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Metoprolol

Generic Name : Metoprolol
Pronunciation : me toe' proe lole
Latest prescription information about Metoprolol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y51.7 | Therapeutic Classification : Beta- Adrenergic Blockers

Trade Names/Brand Names of Metoprolol

India : 


International : 

Lopressor, Toprol XL , Dutoprol

Why is Metoprolol Prescribed? (Indications)

This medication is a beta-blocker, prescribed for high blood pressure either alone or with other medications. It is also used for chest pain, migraine and hyperthyroidism.  It reduces elevated blood pressure by relaxing blood vessels.


When should Metoprolol not be taken? (Contraindications)

Contraindicated in patients with cardiogenic shock, severe heart diseases, anuria (absence of urination) and hypersensitivity.

What is the dosage of Metoprolol?

PO- The recommended dose range is 10 to 300mg/day in divided doses.

How should Metoprolol be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Metoprolol?

• Caution should be exercised in patients with history of heart attack, slow or irregular heartbeat, heart failure, chest pain, poor blood circulation, liver impairment, sugar, breathing problems, adrenal gland tumor (pheochromocytoma), any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

It may cause drowsiness, dizziness, or lightheadedness, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

Avoid abrupt withdrawal.

What are the side effects of Metoprolol?

   Central Nervous System : Tiredness, dizziness, depression, confusion, short-term memory loss, headache, drowsiness, abnormal dreams and sleeplessness.
   Heart : Shortness of breath, slow heart rate, palpitations, heart failure, swelling in the extremities, fainting, chest pain, and low blood pressure.
   Respiratory : Wheezing and difficulty in breathing.
   Gastrointestinal : Diarrhea, nausea, dry mouth, gastric pain, constipation, flatulence, digestive tract disorders, and heartburn.
   Hypersensitive Reactions : Itching or rash.
   Miscellaneous : Musculoskeletal pain, blurred vision, decreased libido, and ringing in the ear.

What are the other precautions for Metoprolol?

Avoid excess dosage.

What are the storage conditions for Metoprolol?

Store it at room temperature and away from light (25C).

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Learn more about Metoprolol's interaction with Food, Herbs, Alcohol and Caffeine

Metoprolol : Frequently Asked Questions

Q: Is it safe to use Metoprolol in elderly patients?

A: Metoprolol is generally safe for use in elderly patients. When metoprolol was administered as monotherapy or in combination with other medications, it was effective in maintaining blood pressure in a majority of elderly hypertensive patients (1 Trusted Source
Safety and efficacy of metoprolol in the treatment of hypertension in the elderly

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Q: Does Metoprolol affect sleep?

A: Metoprolol can pass through the blood-brain barrier (BBB) and have an impact on sleep quality by causing more awakenings and increasing the amount of awake time after onset of sleep (2 Trusted Source
CNS-related side-effects with metoprolol and atenolol

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Q: Can Metoprolol cause a low heart rate?

A: Metoprolol can cause a lowering of the heart rate and cardiac output. In some patients, this will lead to an excessive lowering of the heart rate and result in bradycardia (3 Trusted Source

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Q: Does Metoprolol cause weight gain?

A: Yes, metoprolol causes weight gain as a side effect in the first few months of treatment. Consult a healthcare professional if rapid weight gain occurs while taking this medication (3 Trusted Source

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Q: What happens if Metoprolol is suddenly discontinued?

A: Do not stop taking this medication without consulting a healthcare professional. Sudden withdrawal of the drug may cause withdrawal symptoms like chest pain and a heart attack (4 Trusted Source

Go to source

  • 1. Safety and efficacy of metoprolol in the treatment of hypertension in the elderly - (https://pubmed.ncbi.nlm.nih.gov/1556363/ )
  • 2. CNS-related side-effects with metoprolol and atenolol - ( https://pubmed.ncbi.nlm.nih.gov/4054193/)
  • 3. Metoprolol - ( https://medlineplus.gov/druginfo/meds/a682864.html)
  • 4. Metoprolol - (https://www.ncbi.nlm.nih.gov/books/NBK532923/ )
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devmal, India

TOLOL XR 50 versis Losar 50

Porus45, India

It's important and useful information for bloodpressure patients like me. The tablets sideffect information is also very useful

akbarjah, India

i am taking 50mg metxl morning and 25mg in night.but my bp is uncontrol always near about160/90.
what am i to do to reduce bp.

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