Abiraterone acetate is used along with prednisolone (corticosteroid) for treating a type of prostate cancer called metastatic castration-resistant prostate cancer (mCRPC) previously called hormone-resistant cancer.
It works by blocking the effects of testosterone in the body and suppresses the cancer growth.
Contraindicated in pregnant women and patients with hypersensitivity.
Adult- PO- The recommended dose is 1000mg once daily with prednisone 5mg twice daily.
It comes as a tablet to take by mouth, on an empty stomach.
• Caution should be exercised in patients with history of heart disease, high blood pressure, decrease in blood potassium level, adrenal gland insufficiency, liver or kidney disease, elderly, and in children.
• Monitor liver function, adrenocortical insufficiency, regularly while taking this medication.
• Women who are pregnant or who may be pregnant should not handle ZYTIGA without protection, e.g., gloves.
♦• Most Common: Joint swelling, fracture, liver impairment, decrease in blood potassium level, fluid retention, muscle discomfort, hot flush, diarrhea, urinary tract infection, cough, high blood pressure, abnormal heart rhythm, urinary frequency, night time urination, indigestion and upper respiratory tract infection.
Avoid excess dosage.
Store it at room temperature (20° to 25°C), and in an airtight container.
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