Why is It That Alcohol Use Medications are Not Given to Chronic Liver Disease Patients?

Through this study, the researchers are justifying the need for chronic liver disease patients to use Alcohol use medications. Even these patients with the advanced liver disease should receive treatment for the alcohol-use disorder.

Alcohol use on various forms of the liver disease is being discussed and viewed in this study. The findings of this study are published in the New England Journal of Medicine.

Liver-related mortality is increasing worldwide, due in large part to the increase in alcohol consumption. This review is very timely, as recent epidemiological studies have shown that alcohol consumption that does not reach the risky range is associated with increased morbidity and mortality.

Liver Protein Could Be Used To Treat Alcohol Liver Disease
A protein called fibroblast growth factor 21 (FGF21) helps protect mice against diet-related toxicities to the liver.

‘Alcohol use disorder treatment should be expanded in everyday clinical practice to include patients with the advanced liver disease, concluded the authors’

Below is a summary of the review article:

Alcohol use is common among patients with liver disease and is associated with poor outcomes. In addition, the advanced liver disease can complicate the pharmacologic treatment of alcohol use disorder and alcohol withdrawal syndrome. In fact, medications approved for the alcohol use disorder are prescribed to a minority of patients, yet they could be used by patients with chronic liver disease.

Given that there is no safe threshold for alcohol consumption and, if it exists, it is likely very low, abstinence should be encouraged in patients with the chronic liver disease. In addition, liver transplantation could be considered for patients who abstain from alcohol and present with progressive liver failure.

Alcohol And Relative Diet Intake May Influence Liver Problems
High alcohol preferential mice were found to have lesser liver damage with controlled diet as opposed to chronic binge eating mice who consumed less alcohol

The authors conclude that alcohol use disorder treatment should be expanded in everyday clinical practice to include patients with the advanced liver disease.

Source-Eurekalert

New Regulators of the Most Prevalent Liver Disease Discovered
Novel factors, the AP-1 proteins, which are critically involved in fatty liver disease (FLD) pathogenesis have been identified by scientists.

Risk Factors in Rising Trend of Liver Cancer Identified
Recent studies offer clear picture of the rise of hepatocellular carcinoma or liver cancer.