Color-changing Contact Lens Can Improve Monitoring of Eye Disease Treatments

by Adeline Dorcas on  October 11, 2018 at 12:32 PM Research News
RSS Email Print This Page Comment bookmark
Font : A-A+

Newly developed color-changing contact lens can enhance monitoring of eye disease treatments, reports a new study. The findings of the study are published in the journal ACS Applied Materials & Interfaces.
Color-changing Contact Lens Can Improve Monitoring of Eye Disease Treatments
Color-changing Contact Lens Can Improve Monitoring of Eye Disease Treatments

For all the good they do, eye drops and ointments have one major drawback: It's hard to tell how much of the medication is actually getting to the eye. Scientists report that they have developed a contact lens that changes color as drugs are released. This visual indicator could help eye doctors and patients readily determine whether these medications are where they should be.

Eyes are adept at keeping things out. When something ventures into or toward an eye, the lids blink and tears start rapidly flowing to avoid infection and damage from foreign objects. These processes are usually helpful, but they can hinder the uptake of much-needed medications.

Studies suggest that less than 5 percent of drugs in eye drops and ointments are absorbed, and much of the absorbed medication ends up in the bloodstream instead of the eye, causing side effects.

Contact lenses may be a more effective way to deliver drugs directly to the eye, but real-time monitoring of drug release is still a challenge. So Dawei Deng and Zhouying Xie sought to create a drug-delivering contact lens that would change color as the medication is released into the eye.

The researchers fabricated a color-sensitive contact lens using molecular imprinting, a technique that creates molecular cavities in a polymer structure that match the size and shape of a specific compound, such as a medicine.

In laboratory experiments, the molecularly imprinted contact lenses were loaded with timolol, a drug used to treat glaucoma. Then, the team exposed the lenses to a solution of artificial tears, which was used as a stand-in for the eye.

As the drug was released from the contacts, the architecture of the molecules near the drug changed, which also changed the color in the iris area of the lenses. No dye was involved in the process, reducing possible side effects.

The researchers could see this shift with the naked eye and with a fiber optic spectrometer. They conclude this new lens could control and indicate the sustained release of many ophthalmic drugs.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

Recommended Reading

More News on:

Astigmatism Conjunctivitis Myopia hyperopia Nervous Tic Eye Vision LASIK Surgery Facts Allergy Eye Drops Keratoconus 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive