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Pemphigus - Treatment

Treatment

Pemphigus can be fatal because of the infectious sores and therfore must be treated. Treatment is aimed at:-

  • healing the existing sores
  • reducing the formation of new blisters
  • preventing the formation of autoantibodies 
  • controlling the bodies inflammatory response.

The patient must be constantly monitored by doctors as the drugs that they take can evoke severe side effects.

Some of the treatment modalities include the following:-

  • Administering oral steroids, such as prednisone, is the most common and effective mode of treatment. Adjuvant drugs are given alongside the steroids to avoid the latter’s side effect .
  • Mild cases of pemphigus can be controlled by topical application of steroids
  • Administering gamma globulin intravenously is particularly useful in the case of paraneoplastic pemphigus.
  • Recently, a monoclonal antibody, Rituximab, was found to be particularly effective in controlling very severe types of P. vulgaris.
  • In case of pulmonary disease accompanying paraneoplastic pemphigus immuno suppressive drugs (ciclosporin, azathioprine, thalidomide) are also administered in order to prevent bronchiolitis obliterans
  • Antibiotics may be prescribed to treat infections
  • Gentle cleansing of the wounds and topical application of medications is also mandatory
  • Pain is closely linked to the disease and hence pain management must be resorted to.

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Comments

Eileen64

Is am a breast cancer survivor for 12 years and have had breast sores for 9 nine years it is now sloughing antibotics will not help and I have just recently hadtwo steph infections I been to 4 wound care centers It is sloughing constantly and is painful Any suggestion

siddique44

my daughter is suffering this disease can be cured in india

deepali1218

can you tell when was your daughter digonized of pv and where is she getting treated? how helpful is the treatment? as i am also suffering frm pv since past 1 year. really appreciate your reply

ppjoshi

Dear Readers,

Is there any sure remedy [in any therapy]except administration of "Steroid" based drugs {having equally bad side / after effects}for treating this dreadful skin disease .

Consult Dermatologist Online

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