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Diagnosis of Myasthenia Gravis

Diagnosis of Myasthenia Gravis

Diagnosis is based on clinical features, tests for antibodies, Electromyography (EMG), nerve conduction studies, and clinical response to medications. A detailed history is taken and physical examination is performed.

  • 85% of patients with generalized symptoms have acetylcholine receptor antibodies. A blood test is performed to detect these abnormal antibodies
  • 15% of patients do not test positive for acetylcholine receptor antibodies. Detection of muscle-specific kinase antibodies (anti-MuSK antibodies) is done.
  • Edrophonium (Tensilon) is a chemical which when injected into veins may transiently improve symptoms due to Myasthenia Gravis. This can hence be used as a test.
  • Non specific tests: Electromyography (EMG) studies may reveal characteristic patterns. Single fibre EMG, repeated nerve stimulation, muscle biopsies are also performed.

These tests may be negative in patients even if they have myasthenia gravis.


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Jane511robert - Mar 13, 2023

I had myasthenia gravis since 2017. I got medically discharged out of the Army, a job I loved well. My heart had 5 myasthenic crises, 3 being severe enough to be ventilated or require CPAP [continuous positive airway pressure] helmet. I have had countless plasma exchanges as my veins are bad. I also needed Hickman lines inserted. I have been on azathioprine, mycophenolate (CellCept), methotrexate and none have worked. I'm currently done with my herbal remedy I purchase from Multivitamin herbal cure “ which has totally cured my condition with a surprise after almost 6 months of their usage, I was discouraged and never thought I would be myasthenia gravis (MG) free ,to me the best to get rid of this condition is multivitamincare. org treatment because all medications I used never worked include mycophenolate (CellCept).


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