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Drug information on TENLIPTIN 20 TABLET (Teneligliptin) from Carise Pharmaceuticals Pvt Ltd

TENLIPTIN 20   Tablet Carise Pharmaceuticals Pvt Ltd Generic : Teneligliptin	110.00 20mg + 500mg 10

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Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)

Medically Reviewed by Suchitra Chari, M.S. M.Sc.

Last Updated on May 04, 2018

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Diabetes

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Type 2 Diabetes

• Teneligliptin is a recently developed oral drug used for the treatment of type 2 diabetes in adult patients along with diet and exercise.

•  Gastrointestinal: Abdominal bloating, discomfort or pain, intestinal obstruction, nausea, flatulence, stomatitis, gastric and colon polyps, duodenal ulcer, reflux esophagitis, loss of appetite and diarrhea.

•  Skin: Eczema, rash, itching, allergic dermatitis .

•  Kidney: Urine ketone body, urine glucose and urine protein

•  Respiratory system: Upper respiratory tract infection, nasopharyngitis (inflammation of the throat and nasal passages)

•  Central nervous system: Headache

• The recommended dose for teneligliptin is 20 mg daily.
• The dose can be increased to 40 mg daily if the efficacy is insufficient.

• Teneligliptin should be taken orally once daily.

Teneligliptin is contraindicated in patients with

• Hypersensitivity to the drug or any of the components in the formulation.
• Severe ketosis, type 1 diabetes, severe infection, surgery, severe trauma and diabetic coma or a history of it.

• Use teneligliptin only in patients who have not responded sufficiently to diet and / or exercise therapy alone, or diet and /or exercise therapy with the use of sulfonylureas or thiazolidinediones.
• Caution should be taken while prescribing the drug to patients with advanced liver or congestive heart failure, pituitary or adrenal insufficiency, arrhythmia and with congenital QT prolongation syndrome.
• Use caution when prescribing the drug to pregnant women and infants.
• In patients using an insulin secretagogue like sulfonylurea there is a risk of severe hypoglycemia.
• Complete the entire dose of the drug.

• Avoid excess dose.

• Beta blockers and MAO inhibitors can enhance the blood glucose lowering effect of teneligliptin.
• Steroids and thyroid hormones can attenuate the blood glucose effect of teneligliptin.

• Teneligliptin should be stored at room temperature.