Nucarnit-500mg (Levocarnitine) Drug Price and Information

levocarnitine (Nucarnit-500mg) (Nucarnit-500mg) is prescribed for the prevention and treatment of carnitine deficiency in:
• Primary carnitine deficiency, where the cause of the deficiency is not known
• Secondary carnitine deficiency, due to inborn errors of metabolism like medium chain fatty acylCoA dehydrogenase deficiency.
Other patients who may also suffer from carnitine deficiency and may benefit from levocarnitine treatment include:
• Patients on dialysis with kidney disease. The oral form should not be used in these patients.
• Individuals who take certain medicines such as zidovudine and valproic acid.
levocarnitine (Nucarnit-500mg) (Nucarnit-500mg) is a naturally occurring substance that plays a role in the breakdown of long-chain fatty acids. This process provides energy to the body and also helps to get rid of the excess fats which could be harmful. 
The information provided on this page is intended to serve as a comprehensive resource and should not be a substitute to professional medical advice. If you have concerns it is always best to speak with a healthcare professional.

Nucarnit- - Emcure Pharma

Nucarnit-500mg  Tablet

Generic : Levocarnitine
Price Updated on Jul 08, 2023
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Drug information on Nucarnit-500mg from Emcure Pharma


When is Nucarnit-500mg prescribed?

It is prescribed for -

Overview of Nucarnit-500mg

Levocarnitine is a substance that occurs naturally in the body. It helps the body to use long chain fatty acids as a source of energy.


What should be the dose and frequency?

Oral dosage:
Adults: The maximum oral dose is 990 mg administered in two or three divided doses.
Infants and children: The oral dosage to be started with 50mg/kg/day. The recommended dose is between 50 and 100mg/kg/day in divided doses. The dose should not exceed 3g/day.

Injections dosage for adults and children:
Carnitine deficiency: The normal dose is 50mg/kg bodyweight injected into the vein.
Patients with kidney failure undergoing hemodialysis: The usual dose is 10 to 20 mg/kg bodyweight daily after dialysis.

What are the common side effects of Nucarnit-500mg

GI Tract - Diarrhea, abdominal pain, vomiting, nausea, constipation

Central nervous system - Headache, dizziness, paresthesia (tingling or pricking sensation), taste perversion, seizures

Cardio vascular system - Fluctuations in blood pressure, palpitations, atrial fibrillation and abnormal ECG

Musculoskeletal - Rhabdomyolysis (breakdown of muscle)

Metabolic - Hypertriglyceridemia associated with high doses in dialysis patients, hypercalcemia (high blood calcium levels), hypervolemia

Respiratory - Increase in cough frequency, pharyngitis and breathlessness

Allergic reaction: Rashes, itching. A serious allergic reaction may rarely occur

Others - Depression, fishy body odor, fever

How to use Nucarnit-500mg?

• Levocarnitine is available in the form of tablet, powder and injection. The oral solutions or tablets should be taken with food to avoid a stomach upset.
• If more than one dose is needed in a day, an adequate time interval should be maintained between the doses.


In which conditions should Nucarnit-500mg be avoided?

Levocarnitine should not be taken by patients who develop a severe allergy to the drug.

What are the Precautions needed with Nucarnit-500mg

• In severe kidney disease, accumulation of the drug could occur in patients who consume it for long periods.

• An increase in the frequency of seizures and worsening of existing seizure disorder may occur.

Are there any additional Precautions?

• Avoid excess dose.

Drug Interactions of Nucarnit-500mg

• Levocarnitine could increase the risk of bleeding in patients taking warfarin. Therefore, the patients should be monitored through a regular blood test that measures the warfarin activity (INR or International Normalized Ration).
• Herbal supplements such as ginkgo biloba should be avoided as the combination could increase the risk of seizures.

At What Temperature Should it be Stored?

• Store at room temperature away from light and moisture. Do not freeze.
• Keep out of reach of children.

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