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Zidovudine - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Zidovudine

Generic Name : Zidovudine
Pronunciation : zye doe' vue deen
Latest prescription information about Zidovudine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.5 | Therapeutic Classification : Antiretroviral Agents
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Trade Names/Brand Names of Zidovudine

India : 

More...

International : 

Retrovir
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Why is Zidovudine Prescribed? (Indications)

This medication is an antiretroviral agent, prescribed for HIV/AIDS. It works by decreasing the amount of HIV in the blood.
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When should Zidovudine not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Zidovudine?

Adult- PO- The recommended dose is 600mg/day in divided doses.

How should Zidovudine be taken?

It comes as a capsule and syrup to take by mouth, with or without food.

What are the warnings and precautions for Zidovudine?

Caution should be exercised in patients with history of bone marrow depression, low blood counts, liver, kidney diseases, obesity, any allergy, who are taking other medications, during pregnancy and breastfeeding.

Avoid contact with people who have infections.

Avoid sexual contact with your partner in order to avoid transmission of HIV infection.

Monitor liver, kidney functions, and complete blood cell counts while taking this medication.

What are the side effects of Zidovudine?

   Body as a Whole : Weakness, headache, uneasiness, fever, back, chest pain, flu-like syndrome and generalized pain.
   Gastrointestinal : Loss of appetite, constipation, nausea, vomiting, liver, diarrhea, mouth ulcer, indigestion and flatulence.
   Heart : Heart disease and fainting.
   Blood : Anemia, decrease in white blood cells and platelets.
   Musculoskeletal : Muscle pain/inflammation.
   Central Nervous System : Anxiety, confusion, depression, dizziness, loss of mental acuity, tingling, seizures, drowsiness and unsteadiness.
   Respiratory : Difficulty in breathing, Cough, abnormal breath sounds/wheezing unny nose and sinus inflammation.
   Skin : Changes in skin and nail pigmentation, itching, skin death, rash, hives and increased sweating.
   Eye and ENT : Hearing loss, eye swelling, sensitivity to light and taste perversion.
   Genitourinary : Urinary frequency and urinary hesitancy, breast enlargement in male.

What are the other precautions for Zidovudine?

Avoid excess dosage.

What are the storage conditions for Zidovudine?

Store it at room temperature and away from light.

<>Schedule : HPrescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.



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