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Drug information on Carnisure-500mg (Levocarnitine) from Torrent Pharma

Carnisure-500mg

  Tablet  
Torrent Pharma
Generic : Levocarnitine
 210.00
500mg
10s
Vijayaganesh Kasinathan
Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Sep 26, 2017
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Medical Condition(s) for which Carnisure-500mg may be prescribed


Overview of Carnisure-500mg

Levocarnitine is a substance that occurs naturally in the body. It helps the body to use long chain fatty acids as a source of energy.

Side effects of Carnisure-500mg

  GI Tract - Diarrhea, abdominal pain, vomiting, nausea, constipation

  Central nervous system - Headache, dizziness, paresthesia (tingling or pricking sensation), taste perversion, seizures

  Cardio vascular system - Fluctuations in blood pressure, palpitations, atrial fibrillation and abnormal ECG

  Musculoskeletal - Rhabdomyolysis (breakdown of muscle)

  Metabolic - Hypertriglyceridemia associated with high doses in dialysis patients, hypercalcemia (high blood calcium levels), hypervolemia

  Respiratory - Increase in cough frequency, pharyngitis and breathlessness

  Allergic reaction: Rashes, itching. A serious allergic reaction may rarely occur

  Others - Depression, fishy body odor, fever

Dosage & When it is to be taken (Indications)

Oral dosage:
Adults: The maximum oral dose is 990 mg administered in two or three divided doses.
Infants and children: The oral dosage to be started with 50mg/kg/day. The recommended dose is between 50 and 100mg/kg/day in divided doses. The dose should not exceed 3g/day.

Injections dosage for adults and children:
Carnitine deficiency: The normal dose is 50mg/kg bodyweight injected into the vein.
Patients with kidney failure undergoing hemodialysis: The usual dose is 10 to 20 mg/kg bodyweight daily after dialysis.

How to use Carnisure-500mg?

• Levocarnitine is available in the form of tablet, powder and injection. The oral solutions or tablets should be taken with food to avoid a stomach upset.
• If more than one dose is needed in a day, an adequate time interval should be maintained between the doses.

When is Carnisure-500mg not to be taken? (Contraindications)

Levocarnitine should not be taken by patients who develop a severe allergy to the drug.

Warnings and Precautions for Carnisure-500mg

• In severe kidney disease, accumulation of the drug could occur in patients who consume it for long periods.
• An increase in the frequency of seizures and worsening of existing seizure disorder may occur.

Other Precautions for Carnisure-500mg

• Avoid excess dose.

Drug Interactions of Carnisure-500mg

• Levocarnitine could increase the risk of bleeding in patients taking warfarin. Therefore, the patients should be monitored through a regular blood test that measures the warfarin activity (INR or International Normalized Ration).
• Herbal supplements such as ginkgo biloba should be avoided as the combination could increase the risk of seizures.

Storage Conditions for Carnisure-500mg

• Store at room temperature away from light and moisture. Do not freeze.
• Keep out of reach of children.



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