Tapentadol - Indications, Dosage, Side Effects and Precautions

Last Updated on August 11, 2022
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Information about Tapentadol

Generic Name : Tapentadol
Up-to-date prescription details regarding Tapentadol are provided here.
Pronunciation : ta-PEN-ta-dol
Learn the correct pronunciation of the Tapentadol, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y45 | Therapeutic Classification : Analgesics

Trade Names/Brand Names of Tapentadol

India : 

International : 


Why is Tapentadol Prescribed? (Indications)

This medication is an analgesic, prescribed for moderate to severe acute pain. It works by changing the way the body responds to pain.

When should Tapentadol not be taken? (Contraindications)

Contraindicated in patients with respiratory depression, paralytic ileus, who are taking monoamine oxidase (MAOIs) inhibitors or who have taken MAOIs within the last 14 days, and hypersensitivity.

What is the dosage of Tapentadol?

Adult- PO- The recommended dose is 50 mg, 75 mg, or 100 mg every 4 to 6 hours depending upon pain intensity.

How should Tapentadol be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Tapentadol?

• Caution should be exercised in patients with history of liver or kidney disease, bowel problem, head injury, tumor, stroke, lung or breathing problems, seizure, overweight, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

Avoid alcohol consumption.

Patient may develop with increased risk of seizures; consult with your doctor before taking this medication.

Patient may develop with increased risk of serotonin syndrome with the following symptoms: agitation, confusion, hallucinations, coma, fever, irregular heartbeat, tremor, excessive sweating, nausea, vomiting, or diarrhea. If it is so consult with your doctor.

What are the side effects of Tapentadol?

   Gastrointestinal : Nausea, vomiting, constipation, dry mouth, indigestion, abdominal discomfort and impaired gastric emptying.
   General : Fatigue, feeling hot, irritability, fluid retention, and drug withdrawal syndrome.
   Infections : Upper respiratory tract infection and urinary tract infection.
   Metabolic : Decreased appetite.
   Musculoskeletal : Joint pain, involuntary muscle contractions, and heaviness.
   Central Nervous system : Dizziness, drowsiness, tremor, lethargy, sensory loss, tingling, attention disturbance, sleepiness, speech disorder, unconsciousness, memory loss, incoordination, fainting, epilepsy, sleeplessness, confusion, abnormal dreams, anxiety, disorientation, restlessness, agitation, nervousness, and abnormal thinking.
   Skin : Itching, increased sweating, rash, and hives.
   Heart : Hot flush, increased or decreased heart rate.
   Eye : Visual disturbances.
   Genitourinary : Urinary hesitation and frequent daytime urination.
   Respiratory : Decreased oxygen saturation, cough, difficulty in breathing and respiratory depression.

What are the other precautions for Tapentadol?

Avoid excess dosage.

What are the storage conditions for Tapentadol?

Store it at controlled room temperature (25C), and in an airtight container.
Last Updated : August 11, 2022

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