- Spironolactone - (https://medlineplus.gov/druginfo/meds/a682627.html )
- Long-Term Effects of Spironolactone on Kidney Function and Hyperkalemia-Associated Hospitalization in Patients with Chronic Kidney Disease - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262621/ )
- Short term effects of spironolactone on blood lipid profile: a 3-month study on a cohort of young women with hirsutism - (https://pubmed.ncbi.nlm.nih.gov/19843067/ )
- Spironolactone-Induced Unilateral Gynecomastia - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846220/ )
- Spironolactone as a single agent for long-term therapy of hirsute patients - (https://pubmed.ncbi.nlm.nih.gov/10792338/ )
Information about Spironolactone
Generic Name : SpironolactoneUp-to-date prescription details regarding Spironolactone are provided here.
Pronunciation : speer on oh lak' tone
Learn the correct pronunciation of the Spironolactone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y54.5 Therapeutic Classification : Diuretics
Trade Names/Brand Names of Spironolactone
India :
Fruselac DS |
Laslactone 50 |
Fruselac DS |
Torsid Plus |
Tormax Plus (5mg/50mg) |
Dytor Plus Tab (5mg/50mg) |
Frusis |
Torsid Plus (20 mg) |
Dytor Plus (10mg/50mg) |
Lasilactone 50
International :
Aldactone
Why is Spironolactone Prescribed? (Indications)
This medication is a potassium-sparing diuretic, prescribed for hyperaldosteronism, low potassium levels, and for edema (fluid retention) caused by various conditions. It works by blocking the hormone aldosterone.When should Spironolactone not be taken? (Contraindications)
Contraindicated in patients with anuria (absence of urination), and significant impairment of kidney function.What is the dosage of Spironolactone?
Adult- PO- The recommended dose range is 50 to 400mg/day for 3 to 4 weeks.How should Spironolactone be taken?
It comes as a tablet to take by mouth, with food.What are the warnings and precautions for Spironolactone?
• Caution should be exercised in patients with history of changes in blood minerals, kidney, liver, or heart disease, diabetes or high level of urea or nitrogen in blood, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
What are the side effects of Spironolactone?
Gastrointestinal - Gastric bleeding, ulceration, stomach inflammation, diarrhea, cramping, nausea and vomiting.Genitourinary - Breast enlargement in male, absence of menstrual period, painful erection, irregular periods, breast cancer, kidney impairment and postmenopausal bleeding.
Blood - Decrease in blood counts.
Hypersensitivity - Fever, hives, shock, inflammation of veins and skin lesions.
Metabolic - Elevated blood potassium level.
Central Nervous system - Mental confusion, incoordination, headache, drowsiness and lethargy.
Liver - Liver damage.
What are the other precautions for Spironolactone?
Avoid excess dosage.What are the storage conditions for Spironolactone?
Store it at room temperature (25°C).Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
