This medication is a potassium-sparing diuretic, prescribed for hyperaldosteronism, low potassium levels, and for edema (fluid retention) caused by various conditions. It works by blocking the hormone aldosterone.
Contraindicated in patients with anuria (absence of urination), and significant impairment of kidney function.
Adult- PO- The recommended dose range is 50 to 400mg/day for 3 to 4 weeks.
It comes as a tablet to take by mouth, with food.
• Caution should be exercised in patients with history of changes in blood minerals, kidney, liver, or heart disease, diabetes or high level of urea or nitrogen in blood, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
• Gastrointestinal :
Gastric bleeding, ulceration, stomach inflammation, diarrhea, cramping, nausea and vomiting.
• Genitourinary : Breast enlargement in male, absence of menstrual period, painful erection, irregular periods, breast cancer, kidney impairment and postmenopausal bleeding.
• Blood : Decrease in blood counts.
• Hypersensitivity : Fever, hives, shock, inflammation of veins and skin lesions.
• Metabolic : Elevated blood potassium level.
• Central Nervous system : Mental confusion, incoordination, headache, drowsiness and lethargy.
• Liver : Liver damage.
Avoid excess dosage.
Store it at room temperature (25°C).
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