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Propylthiouracil - Indications, Dosage, Side Effects and Precautions

Propylthiouracil Medication Information

Learn everything you need to know about Propylthiouracil-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Propylthiouracil brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Propylthiouracil
Pronunciation : proe pill thye oh yoor' a sill
ICD Code : Y42.2 Therapeutic Classification : Thyroid and Antithyroid Agents

Brand Names or Trade Names of Propylthiouracil

International :


PTU

Why is Propylthiouracil Prescribed? (Indications)

This medication is an antithyroid agent, prescribed for hyperthyroidism. It stops the thyroid gland from making thyroid hormone.

When should Propylthiouracil not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Propylthiouracil?

Adult: PO- 150-450 mg/day in divided doses. Severe: Initial: 600-1,200 mg/day. Maintenance for euthyroid patients: 50-150 mg/day.

How should Propylthiouracil be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Propylthiouracil?

• Caution should be exercised in patients with history of bone marrow depression; or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• Patient may develop with increased risk of liver damage and bone marrow depression; if it is so consult with your doctor.

• It may affect platelet counts; avoid bruising or injury.

What are the side effects of Propylthiouracil?

Decrease in white blood cells and platelets, lupus-like syndrome, vein inflammation, skin rash, hives, joint pain, fever, GI discomfort, vomiting and headache.

What are the other precautions for Propylthiouracil?

Avoid excess dosage.

What are the storage conditions for Propylthiouracil?

Store it at room temperature.

Propylthiouracil : Frequently Asked Questions

Q: Does Propylthiouracil cause hypothyroidism?

A: Propylthiouracil is used to treat hyperthyroidism, which can cause hypothyroidism. Routine TSH and T4 monitoring is thus required to maintain the euthyroid state(1 Trusted Source
Propylthiouracil (PTU)

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Q: When is the best time to take Propylthiouracil?

A: Propylthiouracil is available as an oral tablet. It is usually administered three times per day, once every eight hours(2 Trusted Source
Propylthiouracil

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).

Q: Who should not take Propylthiouracil?

A: Propylthiouracil is not recommended for patients with a history of hypersensitivity to the drug, hepatic impairment, myelosuppression, or paediatric patients(1 Trusted Source
Propylthiouracil (PTU)

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).

Q: Does Propylthiouracil cause weight gain?

A: The majority of hyperthyroid patients lose weight. Its treatment with antithyroid medications usually results in weight gain(3 Trusted Source
Weight gain following treatment of hyperthyroidism-A forgotten tale

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).

Q: Does Propylthiouracil affect the liver?

A: Propylthiouracil has a black box warning because of the increased risk of severe liver injury and acute liver failure(1 Trusted Source
Propylthiouracil (PTU)

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).



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