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Ptu (Propylthiouracil) Drug Price and Information

Propylthiouracil (Ptu) is an antithyroid agent, prescribed for hyperthyroidism. It stops the thyroid gland from making thyroid hormone.

Ptu - Macleods Pharmaceuticals Ltd

Ptu  Tablet  

Generic : Propylthiouracil
100 Tablets
Price Updated on August 8, 2019
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Drug information on Ptu (Propylthiouracil) from Macleods Pharmaceuticals Ltd

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team

Medical condition(s) for which Ptu may be prescribed


Dosage & When it is to be taken (Indications)

Adult: PO- 150-450 mg/day in divided doses. Severe: Initial: 600-1,200 mg/day. Maintenance for euthyroid patients: 50-150 mg/day.

Side effects of Ptu

Decrease in white blood cells and platelets, lupus-like syndrome, vein inflammation, skin rash, hives, joint pain, fever, GI discomfort, vomiting and headache.

How to use Ptu?

It comes as a tablet to take by mouth, with food.


When Should Ptu not be taken? (Contraindications)



Warnings and Precautions for Ptu

Caution should be exercised in patients with history of bone marrow depression; or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

Patient may develop with increased risk of liver damage and bone marrow depression; if it is so consult with your doctor.

It may affect platelet counts; avoid bruising or injury.

Other Precautions for Ptu

Avoid excess dosage.

Storage Conditions for Ptu

Store it at room temperature.

Ptu(Propylthiouracil) : Frequently Asked Questions

Q: Does Ptu cause hypothyroidism?

A: Ptu is used to treat hyperthyroidism, which can cause hypothyroidism. Routine TSH and T4 monitoring is thus required to maintain the euthyroid state(1 Trusted Source
Propylthiouracil (PTU)

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Q: When is the best time to take Ptu?

A: Ptu is available as an oral tablet. It is usually administered three times per day, once every eight hours(2 Trusted Source

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Q: Who should not take Ptu?

A: Ptu is not recommended for patients with a history of hypersensitivity to the drug, hepatic impairment, myelosuppression, or paediatric patients(1 Trusted Source
Propylthiouracil (PTU)

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Q: Does Ptu cause weight gain?

A: The majority of hyperthyroid patients lose weight. Its treatment with antithyroid medications usually results in weight gain(3 Trusted Source
Weight gain following treatment of hyperthyroidism-A forgotten tale

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Q: Does Ptu affect the liver?

A: Ptu has a black box warning because of the increased risk of severe liver injury and acute liver failure(1 Trusted Source
Propylthiouracil (PTU)

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  • 1. Propylthiouracil (PTU) - (https://www.ncbi.nlm.nih.gov/books/NBK549828/ )
  • 2. Propylthiouracil - (https://medlineplus.gov/druginfo/meds/a682465.html )
  • 3. Weight gain following treatment of hyperthyroidism-A forgotten tale - (https://pubmed.ncbi.nlm.nih.gov/31267667/ )
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