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Olanzapine - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Olanzapine

Generic Name : Olanzapine
Pronunciation : oh lan' za peen
Latest prescription information about Olanzapine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.5 | Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Olanzapine

India : 


International : 


Why is Olanzapine Prescribed? (Indications)

This medication is an atypical antipsychotic, prescribed for schizophrenia.  It changes the activity of certain natural substances in the brain.

When should Olanzapine not be taken? (Contraindications)


What is the dosage of Olanzapine?

PO- Adult The recommended initial dose is 5 to 10 mg once a day. Maintenance: 10 mg/day to 20 mg/day.
Adolescents- The recommended starting dose is 2.5 or 5 mg/day.

How should Olanzapine be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Olanzapine?

Caution should be exercised in patients with history of liver, stomach problems, enlarged prostate, increased eye pressure, neuroleptic malignant syndrome (NMS), lung disease, suicidal thoughts, heart attack, irregular heartbeat, seizures, obesity, breast cancer, difficulty in swallowing, high/low blood pressure, sugar, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.

It may cause dizziness or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

Avoid alcohol consumption.

Drink adequate fluids to avoid becoming over heated or dehydration; otherwise it may cause heat stroke.

It may raise blood sugar with increased thirsty, drowsiness or confusion; if it so consult with your doctor.

Patient may develop Post-injection Delirium Sedation Syndrome (PDSS) within 3 hours after administration of this medication.

What are the side effects of Olanzapine?

   Body as a Whole : Weakness, back pain, accidental injury and chest pain.
   Central Nervous System : Drowsiness, tremor, depression, dizziness, speech disorder, memory loss, tingling, confusion, emotion and incoordination.
   Heart : High blood pressure and fast heart rate.
   Gastrointestinal : Dry mouth, increased appetite/thirst, constipation and increased salivation.
   Metabolic : Weight gain and swelling in the extremities.
   Respiratory : Difficulty in breathing and lung inflammation.
   Skin : Increased sweating, pimples and dry skin.
   Eye : Abnormal vision.
   Genitourinary : Painful menstrual period and vaginal infection.

What are the other precautions for Olanzapine?

Avoid contact with people who have infections.

What are the storage conditions for Olanzapine?

Store it at controlled room temperature (20 - 25C).

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.


gsangia, India

I have been taking olenz rt- 10 for 2 years. I am feeling quite normal . Please advice me how many years I have to take this medicine? ,Thanks Rajeev Sangia email rsangia2000@Gmail.com I m feeiling quite normal

rjsh137, India

I have been taking oliza 10 for 12 years. Please advice me how many years I have to take this medicine? Thanks Rajesh

Somnath_Suri, India

My Sister took Olanex F for 5 mg for 1 year. Though it was prescribed by the doctor for 1 month. She was very thin now become Fat. And now for 15 days she is getting Sense less instantly without getting any indication. We are very much scared for her and confused what to do next? Please advice me to get rid of this problem.

Thanks in advance


grv.bid, India

I take oliza 10 for unused hearing therefore i want to know how many year will be take this medicine for better leving .Plz give me if any alternative way for better solutions.

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