General Information on Disulfiram

Generic Name : Disulfiram

Pronunciation : dye sul' fi ram

Latest prescription information about Disulfiram. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

ICD Code : Y51.1 | Therapeutic Classification : Cholinergic Agents

Trade Names/Brand Names of Disulfiram

India :

International :

Antabuse

Why is Disulfiram Prescribed? (Indications)

This medication is an alcohol antagonist, prescribed for chronic alcoholism. It blocks the processing of alcohol in the body.

When should Disulfiram not to be taken? (Contraindications)

Contraindicated in patients with severe heart disease, mental disorder, who are taking alcohol containing preparations and hypersensitivity.

What is the dosage of Disulfiram?

Adult: PO- 800 mg as a single dose on the 1st day. Reduce dose by 200 mg/day. Maintenance: 100-200 mg/day.

How should Disulfiram be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Disulfiram?

• Caution should be exercised in patients with history of diabetes, thyroid disease, epilepsy, brain damage, kidney or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Monitor liver function and complete blood cell counts regularly while taking this medication.