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Disulfiram - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Disulfiram

Generic Name : Disulfiram
Pronunciation : dye sul' fi ram
Latest prescription information about Disulfiram. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y51.1 | Therapeutic Classification : Cholinergic Agents
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Trade Names/Brand Names of Disulfiram

India : 

International : 

Antabuse
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Why is Disulfiram Prescribed? (Indications)

This medication is an alcohol antagonist, prescribed for chronic alcoholism. It blocks the processing of alcohol in the body.
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When should Disulfiram not be taken? (Contraindications)

Contraindicated in patients with severe heart disease, mental disorder, who are taking alcohol containing preparations and hypersensitivity.

What is the dosage of Disulfiram?

Adult: PO- 800 mg as a single dose on the 1st day. Reduce dose by 200 mg/day. Maintenance: 100-200 mg/day.

How should Disulfiram be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Disulfiram?

Caution should be exercised in patients with history of diabetes, thyroid disease, epilepsy, brain damage, kidney or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

Monitor liver function and complete blood cell counts regularly while taking this medication.

What are the side effects of Disulfiram?

Eye inflammation, peripheral nerve disease, drowsiness, fatigue, impotence, headache and rash.

What are the other precautions for Disulfiram?

Avoid excess dosage.

What are the storage conditions for Disulfiram?

Store it at room temperature (20 to 25C) and in an airtight container. Keep away from moisture and heat.



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Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.

Comments

Ekta8, India

My father is an alcoholic and he refuses to get help. Every single day he drinks and disrupts our entire night. My mother and I are extremely tired and depressed. Can I grind this tablet and dissolve in water and serve him? It will have the same effect or it won't work? Please help.

Manoj_sahu21, India

what is antidose for this drug if I have taken this and getting reactions.

ChrisAvant, United States

Where can I get a copy of the product insert for Disulfram?

kartheekr1, India

how and where i can get these tablets in BANGALORE(INDIA0?i want the cost of the tablets.

mesonu, India

How & where can I get Disulfiram pills (tabs) in kolkata(india)? I would really really appreciate your help.i want to know cost of tablets?



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