Dabigatran - Indications, Dosage, Side Effects and Precautions

Information about Dabigatran

Generic Name : Dabigatran
Up-to-date prescription details regarding Dabigatran are provided here.

Pronunciation : da-bye-GAT-ran

Learn the correct pronunciation of the Dabigatran, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Dabigatran

International :

Pradaxa

Why is Dabigatran Prescribed? (Indications)

This medication is an anticoagulant (blood thinner), prescribed for preventing strokes or serious blood clots in risky patients. It is also used in COVID-19 patients to prevent blood clot formation.

When should Dabigatran not be taken? (Contraindications)

Dabigatran should not be used in patients with

 Allergy to Dabigatran or any of the ingredients
 Patients with active pathological bleeding including bleeding veins, bleeding from peptic ulcer, recent surgeries.

What is the dosage of Dabigatran?

For patients with creatinine clearance (CrCl) > 30 mL/min- The recommended dose is 150 mg taken orally, twice daily.
For patients with CrCl 15-30 mL/min- The recommended dose is 75 mg twice daily.

How should Dabigatran be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Dabigatran?

• Caution should be exercised in patients with history of stomach bleeding, kidney disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

• Avoid abrupt withdrawal; otherwise it may lead to increased risk of stroke.

• Patient may develop with increased risk of bleeding; if it is so consult with your doctor.

What are the side effects of Dabigatran?

Most common- Bleeding in a critical area or organ, indigestion, nausea, upper abdominal pain, gastrointestinal bleeding and diarrhea.
Hypersensitivity- Hives, rash and itching.

What are the other precautions for Dabigatran?

Caution is required in patients with history of

• Stomach bleeding, ulcer
• Kidney disease
• Elderly, children,
• Pregnancy and breastfeeding

What are the Drug Interactions of Dabigatran?

Dabigatran can interact with the following drugs in various extents:

• Rifampicin
• Dronedarone
• Ketoconazole

What are the storage conditions for Dabigatran?

Store it at room temperature (25°C), and in an airtight container. Protect from moisture.

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