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Dabigatran - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Dabigatran

Generic Name : Dabigatran
Pronunciation : da-bye-GAT-ran
Latest prescription information about Dabigatran. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Dabigatran

International- Pradaxa

Why is Dabigatran Prescribed? (Indications)

This medication is an anticoagulant (blood thinner), prescribed for preventing strokes or serious blood clots in risky patients. It is also used in COVID-19 patients to prevent blood clot formation.


When should Dabigatran not be taken? (Contraindications)

Dabigatran should not be used in patients with

 Allergy to Dabigatran or any of the ingredients
 Patients with active pathological bleeding including bleeding veins, bleeding from peptic ulcer, recent surgeries.

What is the dosage of Dabigatran?

For patients with creatinine clearance (CrCl) > 30 mL/min- The recommended dose is 150 mg taken orally, twice daily.
For patients with CrCl 15-30 mL/min- The recommended dose is 75 mg twice daily.

How should Dabigatran be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Dabigatran?

• Caution should be exercised in patients with history of stomach bleeding, kidney disease, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

Avoid abrupt withdrawal; otherwise it may lead to increased risk of stroke.

Patient may develop with increased risk of bleeding; if it is so consult with your doctor.

What are the side effects of Dabigatran?

  Most common: Bleeding in a critical area or organ, indigestion, nausea, upper abdominal pain, gastrointestinal bleeding and diarrhea.
  Hypersensitivity: Hives, rash and itching.

What are the other precautions for Dabigatran?

Caution is required in patients with history of

Stomach bleeding, ulcer
Kidney disease
Elderly, children,
Pregnancy and breastfeeding

What are the Drug Interactions of Dabigatran?

Dabigatran can interact with the following drugs in various extents:


What are the storage conditions for Dabigatran?

Store it at room temperature (25C), and in an airtight container. Protect from moisture.

Dabigatran : Frequently Asked Questions

Q: What happens if Dabigatran is suddenly discontinued?

A: Do not stop taking dabigatran without first consulting your doctor. Stopping dabigatran abruptly may increase your risk of a clot or stroke(1 Trusted Source

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Q: Is Dabigatran an anticoagulant or antiplatelet?

A: Dabigatran belongs to the group of anticoagulants known as direct thrombin inhibitors. It works by preventing the formation of blood clots in the body(1 Trusted Source

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Q: Does Dabigatran increase the risk of bleeding?

A: Dabigatran was linked to an increased risk of gastrointestinal bleeding but a decreased risk of intracranial hemorrhage(2 Trusted Source
Higher Risk of Bleeding with Dabigatran in Atrial Fibrillation

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Q: How should Dabigatran be taken?

A: Dabigatran is a medication that can be taken orally as pellets or capsules. Take dabigatran pellets with soft food or apple juice. Mixing the pellets with milk or foods containing milk products is not recommended(1 Trusted Source

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Q: Does Dabigatran need to be taken with food?

A: The capsules of dabigatran can be taken with or without food. To ensure that your child receives the full dose, give dabigatran pellets before meals. Sprinkle the entire packet of pellets on soft food to prepare a dose of dabigatran pellets(1 Trusted Source

Go to source

  • 1. Dabigatran - (https://medlineplus.gov/druginfo/meds/a610024.html )
  • 2. Higher Risk of Bleeding with Dabigatran in Atrial Fibrillation - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608584/ )
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Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.


Jay81, India

Paradaxa medicine is expensive. 110mg costs above Rs 700 in India. A monthly dose costs over 4000. Any alternate brands for same active ingredient?

Ishwr, India

Who are the Suppliers in India please
What is the approximate price
What is the shelf life, considering the warm climate
many Thanks

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