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Codeine - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Codeine

Generic Name : Codeine
Pronunciation : KOE deen
Latest prescription information about Codeine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y55.4 | Therapeutic Classification : Expectorant and Cough Products

Trade Names/Brand Names of Codeine

India : 


International : 

Fioricet With Codeine, Floricet With Codeine, Phrenilin With Caffeine And Codeine

Why is Codeine Prescribed? (Indications)

This medication is a narcotic analgesic, prescribed for pain and cough. It is also used for diarrhea. 


When should Codeine not be taken? (Contraindications)


What is the dosage of Codeine?

Adult: PO- Pain- 30-60 mg 4 hourly. Max: 240 mg/day.
Cough suppressant- 15-30 mg 3-4 times/day. Max: 240 mg/day.
Acute diarrhea- 30 mg 3-4 times/day.
IV/IM/SC- Pain- 30-60 mg 4 hourly. Max: 240 mg/day.

How should Codeine be taken?

It comes as syrup to take by mouth, with or without food.

What are the warnings and precautions for Codeine?

• Caution should be exercised in patients with history of head injury; brain tumor, epilepsy, mental illness; lung diseases, breathing problems, prostate enlargement, urinary problems, low blood pressure, Addison’s disease, allergies, thyroid, pancreatic, intestinal, gallbladder, liver or kidney disease and during pregnancy and lactation.

• Reduce dose in elderly or debilitated patients.

• It may cause dizziness, lightheadedness, or drowsiness, do not drive a car or operate machinery while taking this medication, and get up slowly from bed.

• Avoid alcohol consumption while taking this medication.

What are the side effects of Codeine?

  Most Common: Lightheadedness, dizziness, sedation, nausea, vomiting and sweating.
  Central Nervous System: Elevated mood, anxiety, weakness, headache, sleeplessness, agitation, disorientation and visual disturbances.
  Gastrointestinal: Dry mouth, loss of appetite, constipation and biliary tract spasm.
  Heart: Flushing of the face, slow heart rate, palpitation and fainting.
  Genitourinary: Urinary retention or hesitancy, absence of urination, reduced sexual activity and/or potency.
  Allergic: Itching, hives, rash, swelling and rarely bleeding.

What are the other precautions for Codeine?

Take proper diet, otherwise it may lead to constipation.

What are the storage conditions for Codeine?

Oral: Store it at controlled room temperature (15-30°C).

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
Last Updated : 2/28/2023
Learn more about Codeine's interaction with Food, Herbs and Alcohol

Codeine : Frequently Asked Questions

Q: Is Codeine an addictive drug?

A: Yes, it is possible to become addicted to codeine. Always follow the instructions given by a healthcare professional to reduce the risk of becoming addicted (1 Trusted Source
Opioid Use Disorder

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Q: Does Codeine help to reduce coughing?

A: Codeine helps reduce coughing by changing the way the brain responds to pain and decreasing activity in the part of the brain that causes coughing (2 Trusted Source
FDA Drug Safety Communication: FDA evaluating the potential risks of using codeine cough-and-cold medicines in children

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Q: What are the available dosage forms of Codeine?

A: The available dosage forms of codeine include a tablet, a capsule, and an oral solution (3 Trusted Source
Codeine : Medlineplus

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Q: Does Codeine cause constipation?

A: Codeine belongs to the class of opioid analgesics. The most common adverse effect of opioid use is constipation (4 Trusted Source
The Useage of Opioids and their Adverse Effects in Gastrointestinal Practice: A Review

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Q: Is Codeine safe to use in kidney impairment patients?

A: Codeine can be given to patients with renal impairment, but clinicians should prescribe this medication at a lower-than-normal dose or with longer dosing intervals (5 Trusted Source

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Medindia adheres to strict ethical publishing standards to provide accurate, relevant, and current health content. We source our material from reputable places such as peer-reviewed journals, academic institutions, research bodies, medical associations, and occasionally, non-profit organizations. We welcome and value audience feedback as a part of our commitment to health literacy and informed decision-making.
  • 1. Opioid Use Disorder - (https://www.ncbi.nlm.nih.gov/books/NBK553166/ )
  • 2. FDA Drug Safety Communication: FDA evaluating the potential risks of using codeine cough-and-cold medicines in children - (https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-evaluating-potential-risks-using-codeine-cough-and-cold-medicines )
  • 3. Codeine : Medlineplus - (https://medlineplus.gov/druginfo/meds/a682065.html )
  • 4. The Useage of Opioids and their Adverse Effects in Gastrointestinal Practice: A Review - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990131/ )
  • 5. Codeine - (https://www.ncbi.nlm.nih.gov/books/NBK526029/ )
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amit8, India

sir, i have a need of 10 c/s of codiene phosphate

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