Information about Clofarabine

Generic Name : Clofarabine
Up-to-date prescription details regarding Clofarabine are provided here.

Pronunciation : kloe-FAR-a-been

Learn the correct pronunciation of the Clofarabine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Clofarabine

International :

Clolar

Why is Clofarabine Prescribed? (Indications)

This medication is a form of antimetabolite chemotherapy, prescribed for leukemia in children and adolescents. It kills existing cancer cells and limits the development of new cancer cells.

When should Clofarabine not be taken? (Contraindications)

Contraindicated in patients who are taking medications that may affect kidney and liver, and hypersensitivity.

What is the dosage of Clofarabine?

Child- IV- The recommended dose and schedule is 52 mg/m² over 2 hours infusion daily for 5 consecutive days.

How should Clofarabine be taken?

It comes as a solution for injection to be administered by a healthcare provider.

What are the warnings and precautions for Clofarabine?

• Caution should be exercised in patients with history of hematopoietic stem cell transplant (HSCT), low blood pressure, heart, liver or kidney disease, bone marrow depression, any allergy, who are taking other medications, during pregnancy and breast-feeding.

• It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Monitor blood counts, blood pressure, lung function, liver function, kidney function, and blood uric acid levels regularly while taking this medication.

What are the side effects of Clofarabine?

Most Common - Gastrointestinal tract symptoms, including vomiting, nausea, and diarrhea.
Blood - Anemia, decrease in white blood cells and transfusion reaction.
Heart - Fast heart rate, flushing and high blood pressure.
♦ Gastrointestinal - Abdominal pain, constipation, diarrhea, gum bleeding, nausea, sore throat, vomiting, GI bleeding.
General - Fluid retention, fatigue, injection site pain, lethargy, fever and rigors.
Liver - Liver enlargement and jaundice.
Metabolic - Loss of appetite and decreased weight.
Musculoskeletal - Joint/muscle pain, back pain and pain in limb.
Central Nervous System - Dizziness, headache, drowsiness, tremor, anxiety, depression and irritability.
Genitourinary - Blood in urine.
Respiratory - Cough, difficulty in breathing, nose bleed and respiratory distress.
Skin - Contusion, skin inflammation, dry skin, redness, blister and itching.