• Choline is a water-soluble essential nutrient produced in the liver in humans.
• It is naturally present in some foods and also available as a dietary supplement.
Choline is prescribed to pregnant women to prevent neural tube defects in offspring. It is used as a supplement in infant formulas to promote brain growth and intelligence.
Choline may help reduce the severity and the number of asthma attacks. There is some evidence that higher doses (3 g per day for adults) work better than lower doses.
Since choline deficiency causes muscle damage and abnormal deposition of fat in the liver, which results in a condition called nonalcoholic fatty liver disease, it could possibly be used to treat the condition.
Choline is consumed by athletes for bodybuilding and to delay fatigue in endurance sports.
Choline’s other benefits include treatment of depression and memory loss.
Choline could prevent cancer, and help in lowering cholesterol.
Although humans can synthesize choline in small amounts, it must be consumed in the diet to maintain health. Most of the body's choline is found in specialized fat molecules known as phospholipids, the most common of which is called phosphatidylcholine. It is found in foods like meat, eggs, poultry, fish, dairy products, potatoes, cruciferous vegetables, some bean, nuts and seeds.
• Choline is contraindicated if the patients are allergic to the supplement or the foods that contain choline.
• The recommended adequate intake (AI) dosage of choline per day is as follows:
Men – 550 mg
Women – 425 mg
Pregnant women – 450 mg
Breast feeding women – 550 mg
Infants and babies - 125- 150 mg
Children 1-3 years - 200 mg per day; 4-8 years - 250 mg per day; 9-13 years - 375 mg per day
• The Daily Upper Intake Levels (UL) fixed for the various groups are :
1 gram daily for children 1-8 years, 2 grams for children 9-13 years, 3 grams for children 14-18 years, and 3.5 grams for adults over 18 years of age.
• One Capsule of choline should be taken before breakfast or lunch.
• Choline should be consumed at appropriate doses and not higher than the Daily Upper Intake Levels to prevent side effects in all the groups.
• Choline taken at doses higher than the Daily Upper Intake Levels might cause sweating, a fishy body odor, blood pressure lowering, gastrointestinal distress, diarrhea, and vomiting.
• Caution should be taken while taking choline while you are pregnant.
• There is no known drug interaction with choline.
• Choline should be stored at room temperature.
• Keep it out of reach from children.
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