Bosentan Medication Information

Learn everything you need to know about Bosentan-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Bosentan brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Bosentan

Pronunciation : boe sen' tan

ICD Code : Y52.3 Therapeutic Classification : Vasodilators

Brand Names or Trade Names of Bosentan

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International :

Tracleer

Why is Bosentan Prescribed? (Indications)

This medication is an endothelin receptor antagonist, prescribed for pulmonary atrial hypertension (high blood pressure in the lungs). The medication blocks the effects of endothelin-1 thereby decreases blood pressure in lungs. The medication also inhibits blood vessel thickening.

When should Bosentan not be taken? (Contraindications)

Contraindicated in pregnant women, co-administration with cyclosporine A and glyburide may increase the risk of liver damage; hypersensitivity.

What is the dosage of Bosentan?

Initial: The recommended dose is 62.5 mg twice daily for 4 weeks. Maintenance dose is 125 mg twice daily.

How should Bosentan be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Bosentan?

• Caution should be exercised in patients with history of heart disease, liver disease and anemia.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• During the treatment monitor the level of hemoglobin regularly.

• Avoid pregnancy while taking this medication by using proper birth control methods.

• ♦Patient may develop oligohidrosis(absence of sweating) or high body temperature. If it is so consult with your healthcare provider.

What are the side effects of Bosentan?

Most Common- Respiratory tract infection, nausea, stomach pain, loss of appetite, chest pain, fainting, low blood pressure, palpitation and anemia.
Central Nervous System - Headache, dizziness and tiredness.
Gastrointestinal- Diarrhea.
Genitourinary - Reduced sperm count.
Miscellaneous- Liver failure, rash, jaundice and joint pain.