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General Information on Bendamustine hydrochloride

Generic Name : Bendamustine hydrochloride

Pronunciation : BEN-da-MUS-teen HYE-droe-KLOR-ide

Latest prescription information about Bendamustine hydrochloride. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Bendamustine hydrochloride

India : 

International : 

Treanda

Why is Bendamustine hydrochloride Prescribed? (Indications)

This medication is an alkylating agent, prescribed for chronic lymphocytic leukemia (CLL), and non-Hodgkin lymphoma (NHL). It kills existing cancer cells and limits new cancer cells growth.

When should Bendamustine hydrochloride not to be taken? (Contraindications)

Contraindicated in patients with severe kidney disease, and hypersensitivity.

What is the dosage of Bendamustine hydrochloride?

IV- The recommended dose is 100 mg/mē over 30 minutes infusion on Days 1 and 2 of a 28-day cycle, up to 6 cycles.

How should Bendamustine hydrochloride be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Bendamustine hydrochloride?

• Caution should be exercised in patients with history of infection, liver or kidney problems, other types of cancer, bone marrow depression, any allergy, who are taking this medications, children during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid contact with people who have infections.

• Avoid live vaccinations during the treatment period.

• Monitor liver, kidney function, uric acid level, complete blood count, blood chemistry regularly while taking this medication.

What are the side effects of Bendamustine hydrochloride?

•   Most Common : Fever, nausea and vomiting, weakness, fatigue, uneasiness, dry mouth, drowsiness, cough, constipation, headache and mouth ulcer.
•   Heart : Fast heart rate and low blood pressure.
•   Gastrointestinal : Nausea, vomiting, diarrhea, constipation, mouth ulcer, abdominal pain, indigestion, gastroesophageal reflux disease and dry mouth.
•   General : Fatigue, fever, chills, swelling in the extremities, weakness, infections, chest pain and injection site pain.
•   Metabolic : Loss of appetite, dehydration, decreased potassium level in blood and decrease in weight.
•   Musculoskeletal : Back pain, joint pain, pain in extremity and bone pain.
•   Central Nervous system : Headache, dizziness, sensory loss, sleeplessness, anxiety and depression.
•   Respiratory : Cough, difficulty in breathing, wheezing and nose congestion.
•   Skin : Rash, itching, dry skin, night sweats and acidity.

What are the other precautions for Bendamustine hydrochloride?

Avoid excess dosage.

What are the storage conditions for Bendamustine hydrochloride?

Store it in room temperature (25°C).

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