Adalimumab is prescribed to treat autoimmune disorders such as rheumatoid arthritis, ulcerative colitis, Crohn's disease, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis.
It works by inhibiting a specific cell signal protein that causes inflammation.
SC- The recommended dose is 40mg to 80 mg, every two weeks; it may be increased if needed.
Juvenile Idiopathic Arthritis- 15 kg (33 lbs) to <30 kg (66 lbs): 20 mg every two weeks ≥30 kg (66 lbs): 40 mg every two weeks.
It comes as a solution to inject under the skin (subcutaneous), by a healthcare provider.
Infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body , liver failure, blood clot in the lung, cerebrovascular accident, and cancer.
• Most common: Injection site reactions, fever, joint pain, numbness, tingling and swelling in the face, tongue, ankles and lower leg regions, headache, rash, nausea and stomach upset.
• Respiratory : Upper respiratory tract infection, asthma, sinusitis and flu syndrome.
• Gastrointestinal : Feeling full, loss of appetite, pain in you’re the upper stomach that may spread to the shoulder.
• Skin : Redness, rash, itching, bruising and pus filled skin eruptions.
• Central Nervous System : Dizziness, confusion and tremor.
• Respiratory : Difficulty in breathing.
• Heart : Cardiovascular disorder, chest pain and heart attack.
• Eye : Vision problems (cataract).
• Laboratory Test: High cholesterol in blood, reduced levels of platelets and red cells, blood in urine and increase in the liver enzymes.
• Miscellaneous : Accidental injury, back pain, urinary tract infection, weight loss, tiredness and high blood pressure.
Avoid vaccination while taking this medication.
Refrigerate at 36°F to 46°F (2°C to 8°C) in an airtight container. Do not freeze. Do not use if frozen even if it has been thawed. When traveling, store HUMIRA in a cool carrier with an ice pack. Protect from light.