This medication is a tumor necrosis factor alpha (TNF alpha) inhibitor, prescribed for rheumatoid arthritis, crohn's disease (digestive tract inflammation), psoriatic arthritis, ulcerative colitis, plaque psoriasis, ankylosing spondylitis (spine infammation), and juvenile idiopathic arthritis (joint inflammation in children). It blocks the effect of TNF and thereby reduces the inflammation and its consequences in the joints and intestine.
SC- The recommended dose is 40mg to 80 mg, every two weeks; it may be increased if needed.
Juvenile Idiopathic Arthritis- 15 kg (33 lbs) to <30 kg (66 lbs): 20 mg every two weeks ≥30 kg (66 lbs): 40 mg every two weeks.
It comes as a solution to inject under the skin (subcutaneous), by a healthcare provider.
It may cause serious infection, which leads to death, contact your healthcare provider immediately if you have any signs of infection such as fever, cough, or flu-like symptoms.
Perform lab test for tuberculosis before treatment. Monitor every patient for active tuberculosis while taking this medication.
Tuberculosis treatment should be given prior to this medication.
In some patients it may develop cancer like lymphoma.
Caution should be exercised in patients with cancer, multiple sclerosis, heart disease, during pregnancy and breastfeeding.
Infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body , liver failure, blood clot in the lung, cerebrovascular accident, and cancer.
Most common: Injection site reactions, fever, joint pain, numbness, tingling and swelling in the face, tongue, ankles and lower leg regions, headache, rash, nausea and stomach upset.
Respiratory : Upper respiratory tract infection, asthma, sinusitis and flu syndrome.
Gastrointestinal : Feeling full, loss of appetite, pain in youre the upper stomach that may spread to the shoulder.
Skin : Redness, rash, itching, bruising and pus filled skin eruptions.
Central Nervous System : Dizziness, confusion and tremor.
Respiratory : Difficulty in breathing.
Heart : Cardiovascular disorder, chest pain and heart attack.
Eye : Vision problems (cataract).
Laboratory Test: High cholesterol in blood, reduced levels of platelets and red cells, blood in urine and increase in the liver enzymes.
Miscellaneous : Accidental injury, back pain, urinary tract infection, weight loss, tiredness and high blood pressure.
Avoid vaccination while taking this medication.
Refrigerate at 36°F to 46°F (2°C to 8°C) in an airtight container. Do not freeze. Do not use if frozen even if it has been thawed. When traveling, store HUMIRA in a cool carrier with an ice pack. Protect from light.
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