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Abatacept - Indications, Dosage, Side Effects and Precautions

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Information about Abatacept

Generic Name : Abatacept
Up-to-date prescription details regarding Abatacept are provided here.

Pronunciation : a ba ta' sept

Learn the correct pronunciation of the Abatacept, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y45.4 Therapeutic Classification : Antirheumatics

Trade Names/Brand Names of Abatacept

International :


Orencia

Why is Abatacept Prescribed? (Indications)

Abatacept modifies the immune system in patients with rheumatoid arthritis who were not benefited from other treatments.

Abatacept blocks the activity of a type of immune cell responsible for causing damage and swelling to the joints.

When should Abatacept not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Abatacept?

Dose is based on body weight and condition of the patient. Weight < 60 kg should receive 500 mg dose, weight 60-100 kg a 750 mg dose and weight >100 kg a 1000 mg dose.
Juvenile Idiopathic Arthritis- Pediatric patients weighing less than 75 kg: receive 10 mg/kg.

How should Abatacept be taken?

It is administered as an injection into the vein (intravenously), or as a solution for subcutaneous (under the skin) injection by a healthcare provider every 2 weeks for the first 3 doses and then every 4 weeks.

What are the warnings and precautions for Abatacept?

• Patient may develop with serious infections and tumor. Caution should be exercised in patients with history of lung, nerve diseases (e.g. multiple sclerosis), cancer, Human Immunodeficiency Virus (HIV), tuberculosis (TB), severe combined immunodeficiency syndrome (SCID), cut or open sore, diabetes (especially if you are checking your blood sugar level at home), during pregnancy and breastfeeding.

• Avoid vaccination while taking this medication.

What are the side effects of Abatacept?

Serious- Infection and cancer.
Central Nervous System - Headache and dizziness.
Respiratory - Upper respiratory tract infection and inflammation of nasopharynx.
Gastrointestinal - Nausea, indigestion and severe abdominal pain.
Skin - Rash, red or painful skin, hives.
Miscellaneous- Cough, fever, tiredeness, flu-like symptoms, or warm, swelling of the eyes, face, lips, tongue, or throat, back pain, high blood pressure, indigestion, heartburn, night sweats, urinary tract infection, change in the amount of urine and pain in arms and legs.
Side effects in children - Upper respiratory tract infection, inflammation of nasopharynx, headache, nausea, diarrhea, cough and abdominal pain.

What are the other precautions for Abatacept?

Avoid excess dosage.
It should not be used as a first-line drug for the treatment.

What are the storage conditions for Abatacept?

Normally handled and stored by healthcare providers in refrigerator. Do not freeze and keep it away from light.
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