Desmopressin - Drug Information

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General Information on Desmopressin

Generic Name : Desmopressin

Pronunciation : des moe press' in

Latest prescription information about Desmopressin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42 | Therapeutic Classification : Hormones

Trade Names/Brand Names of Desmopressin

India : 

International : 

DDAV

Why is Desmopressin Prescribed? (Indications)

This medication is an antidiuretic synthetic hormone, prescribed for primary nocturnal enuresis (nighttime bedwetting). It is also used for coagulation disorders and diabetes.  

When should Desmopressin not to be taken? (Contraindications)

Contraindicated in patients with severe kidney disease, low blood sodium level and hypersensitivity.

Pregnancy Category

A B C D X

Category B :

Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.

What is the dosage of Desmopressin?

Hemophilia A and von Willebrand's Disease- IV- The recommended dose is 4mcg/ml at a dose of 0.3 mcg DDAVP/kg body weight diluted in sterile physiological saline and infused slowly over 15 to 30 minutes.
Diabetes Insipidus: IV/SC- The usual dosage range in adults is 0.5 mL (2.0 mcg) to 1 mL (4.0 mcg) daily.
Adult: PO- The recommended initial dose is 100 mcg 3 times/day.

How should Desmopressin be taken?

It comes as a tablet to take by mouth, with or without food. It also comes as a solution for injection to be administered by a healthcare provider into the vein or muscle.

What are the warnings and precautions for Desmopressin?

Caution should be exercised in patients with history of kidney, heart, liver disease, high blood pressure, dehydration, fever, severe infection, vomiting, diarrhea, electrolyte imbalance, drowsiness, any allergy, who are taking other medications, elderly, children especially for children less than 6 years old, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
It may lead to dehydration; drink adequate fluid.
Patient may develop with infections, fever, vomiting or diarrhea; if it is so consult with your doctor.

What are the side effects of Desmopressin?

Headache, nausea, flushing and mild abdominal cramps.

What are the other precautions for Desmopressin?

Avoid excess dosage.

What are the storage conditions of Desmopressin?

Store it at controlled room temperature 20 to 25C and in an airtight container. Keep away from children. Store the liquid in the refrigerator, do not freeze it.

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