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Desmopressin

Latest prescription information about Desmopressin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Desmopressin
Pronunciation : des moe press' in
Trade Name(s): 
India- Des-Press Inhalation Soln, D-Pressin Nasal Spray, D-Pressin Tab, D-Void N-Spray, Minirin Inj, Minirin Nasal Spray, Minirin Tab.
International- DDAV.
Why it is prescribed (Indications) : 
This medication is an antidiuretic synthetic hormone, prescribed for primary nocturnal enuresis (nighttime bedwetting). It is also used for coagulation disorders and diabetes.

When it is not to be taken (Contraindications): 


Contraindicated in patients with severe kidney disease, low blood sodium level and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Hemophilia A and von Willebrand's Disease- IV- The recommended dose is 4mcg/ml at a dose of 0.3 mcg DDAVP/kg body weight diluted in sterile physiological saline and infused slowly over 15 to 30 minutes.
Diabetes Insipidus: IV/SC- The usual dosage range in adults is 0.5 mL (2.0 mcg) to 1 mL (4.0 mcg) daily.
Adult: PO- The recommended initial dose is 100 mcg 3 times/day.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food. It also comes as a solution for injection to be administered by a healthcare provider into the vein or muscle.
Special Instruction : 
* Caution should be exercised in patients with history of kidney, heart, liver disease, high blood pressure, dehydration, fever, severe infection, vomiting, diarrhea, electrolyte imbalance, drowsiness, any allergy, who are taking other medications, elderly, children especially for children less than 6 years old, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It may lead to dehydration; drink adequate fluid.
* Patient may develop with infections, fever, vomiting or diarrhea; if it is so consult with your doctor.
Side Effects : 
Headache, nausea, flushing and mild abdominal cramps.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature 20 to 25°C and in an airtight container. Keep away from children. Store the liquid in the refrigerator, do not freeze it.

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