In cortical neurons, hypoxia-inducible factor 1 (HIF-1) attenuates amyloid-beta protein neurotoxicity and decreases apoptosis induced by oxidative stress or hypoxia.
Researchers Develop Patient-Specific Stem Cells and Personalized Gene Therapy
Researchers from Columbia University Medical Center (CUMC) have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.
Researchers from Columbia University Medical Center (CUMC) have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.
With these investigations published in the Neural Regeneration Research (Vol. 9, No. 11, 2014), gene therapy using rAAV to deliver HIF-1α may ultimately provide a new option for clinical treatment of Alzheimer's disease.
Source-Eurekalert
Regeneration of Retinal Ganglion Cell Axons and Gene Therapy
The adult mammalian central nervous system has only limited intrinsic capacity to regenerate connections after injury.
The adult mammalian central nervous system has only limited intrinsic capacity to regenerate connections after injury.
Cellular Mechanism Involved in Memory Consolidation may Develop Gene Therapy
The first cause of dementia is Alzheimer's disease and it affects some 400,000 people in Spain alone. However, no effective cure has been found till now.
The first cause of dementia is Alzheimer's disease and it affects some 400,000 people in Spain alone. However, no effective cure has been found till now.
Bionic Ear Technology Used for Gene Therapy may Help Restore Hearing Quality
New research suggests that the quality of hearing among people who have impaired hearing can be improved by using bionic ear technology.
New research suggests that the quality of hearing among people who have impaired hearing can be improved by using bionic ear technology.
