About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Researchers Capture Fertilization Process for First Time Ever

by Dr. Trupti Shirole on February 29, 2016 at 10:39 PM
Font : A-A+

 Researchers Capture Fertilization Process for First Time Ever

Shedding some light on the still-mysterious process of fertilization, researchers have captured highly detailed images of what happens when sperm and egg first touch.

Researcher Benjamin Ravaux and his colleagues work in collaboration with biologists and physicians involved in fertilization and assisted reproduction technologies such as in vitro fertilization (IVF), developing multidisciplinary tools that will help to elucidate fertilization in mammals.

Advertisement


To that end, Ravaux designed a new microfluidics device that allows him to precisely control the membrane location where a sperm cell fuses with an egg. The device consists of a microfluidic chip made from a multilayer silicon polymer sealed on a glass slide; a sperm cell is located in the bottom layer and the egg is positioned in the top, inside an eggcup. At the bottom of the eggcup is a tiny opening, 30 millionths of a meter wide, forming a connection to the chip's lower layer. When added to the lower layer, the sperm cell swims through the opening and adheres to, fuses with, and fertilizes the egg. The chip is compatible with optical imaging technologies such as confocal microscopy, allowing the researchers to obtain high-resolution images and movies of the fertilization process, as it occurs.

"This is a completely new approach," Ravaux said. With the device, the researchers were able to obtain the first images with both high spatial and temporal resolution of the onset of contact between a single sperm and egg, the merger of their membranes, and the engulfment of the sperm by the egg. In addition, they were able to observe the incorporation of sperm DNA inside the cytoplasm of the egg.
Advertisement

"Our approach has the potential to provide new knowledge in a research field that remains largely under-explored because of a lack of adequate technologies. This 'IVF chip' is a unique tool to observe the cascade of molecular and membrane events occurring during the fertilization process," Ravaux said.

The new technique will be described in a talk at the Biophysical Society's 60th annual meeting at the Los Angeles Convention Center in Los Angeles, Calif.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Know More About Mitochondria
Top 10 Foods for Decreasing DHT Production and Preventing Hair Fall
Alarming Cesarean Section Trends in India - Convenience or Compulsion of Corporate Healthcare
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Artificial Insemination 

Most Popular on Medindia

The Essence of Yoga Accident and Trauma Care Calculate Ideal Weight for Infants Sanatogen Pregnancy Confirmation Calculator Drug - Food Interactions Find a Doctor Selfie Addiction Calculator Nutam (400mg) (Piracetam) Daily Calorie Requirements
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Researchers Capture Fertilization Process for First Time Ever Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests