Physical Activity Interventions may not Influence the Onset of Dementia

Prescribed medications, Physical activity and over the counter vitamins may not slow down the onset of cognitive impairment or dementia in adults.

Interventions such as medications, physical activity, and vitamins supplements may not prevent the onset dementia in older adults. The finding of this study is further discussed in the Journal of Annals of Internal Medicine.

The //prevalence of cognitive impairment and dementia is expected to increase dramatically as the population ages. Optimal treatment to prevent or delay cognitive decline, mild cognitive impairment, or Alzheimer-type dementia is not known. EPC researchers were funded by the Agency for Healthcare Research and Quality (AHRQ) to assess the literature and determine if any interventions had enough quality evidence to warrant a recommendation.

Physical Activity Boosts Cognition in Breast Cancer Survivors
Women who exercise have a significant improvement in cognitive processing speed and some improvements in their perceived mental abilities.

‘An intervention to practice a healthy lifestyle earlier in life can protect against cognitive decline or dementia in later life and may also provide other noncognitive benefits.’

Physical Activity

Researchers reviewed data from 16 trials comparing a physical activity intervention with an inactive control. They found insufficient evidence to conclude the effectiveness of aerobic training, resistance training, or tai chi for improving cognition. The researchers did find low-strength evidence that is combining different types of interventions at the same time, such as physical activity, diet, and cognitive training, improved cognitive test performance.

Prescription Medications

Cancer Survivors Can Also Benefit From Physical Activity
Regular physical activity helps improve overall health and fitness, and also doubled the breast cancer survivors's post-treatment mental processing speed.

Researchers reviewed data from 51 trials comparing the effect of prescription medication with placebo, usual care, or active control on cognitive outcomes. The evidence did not support use of any of the studied pharmacologic treatments (dementia medications, antihypertensives, diabetes medications, NSAIDs or aspirin, hormones, and lipid-lowering agents) for cognitive protection in persons with normal cognition or mild cognitive impairment.

Cognitive Training

Physical Activity Reduces Cardiovascular Risk in Elderly
Any type of physical activity is much better to reduce cardiovascular risk in the elderly. Modest levels of regular physical activity are good for heart health.

A review of 11 trials of adults with either normal cognition or mild cognitive impairment at the time of enrollment found that insufficient evidence that cognitive training exercises could prevent dementia. Group cognitive training was found to improve performance only in the cognitive domain trained. For example, memory training improved memory but did not improve any other aspects of cognition.

Over-the-counter Vitamins and Supplements

Health Apps in iPhone Might Underestimate Physical Activity of Users
Accelerometers used in the smartphone app were found to underestimate the number of steps a person walks in a day.

The study authors reviewed 38 trials comparing over-the-counter (OTC) supplements, including omega-3 fatty acids, soy, ginkgo biloba, B vitamins, vitamin D plus calcium, vitamin C or beta-carotene, multi-ingredient supplements, with placebo or other OTC interventions for preventing or delaying cognitive decline, mild cognitive impairment, or clinical Alzheimer-type dementia. They found insufficient evidence to suggest that any of the supplements worked to reduce the risk for cognitive decline.

According to the researchers, the reasons these interventions fail is not entirely clear. It is possible that they simply do not work to improve cognition, or it could also be that the studies started the interventions too late in life, didn’t use them long enough, or because of shortcomings in many of the studies.

Researchers note that while there was no evidence about whether an intervention to practice a healthy lifestyle earlier in life protects against cognitive decline or dementia in later life, it is unlikely to worsen cognition and may have other, noncognitive benefits.

Source-Eurekalert