Interventions such as medications, physical activity, and vitamins supplements may not prevent the onset dementia in older adults. The finding of this study is further discussed in the Journal of Annals of Internal Medicine. The //prevalence of cognitive impairment and dementia is expected to increase dramatically as the population ages. Optimal treatment to prevent or delay cognitive decline, mild cognitive impairment, or Alzheimer-type dementia is not known. EPC researchers were funded by the Agency for Healthcare Research and Quality (AHRQ) to assess the literature and determine if any interventions had enough quality evidence to warrant a recommendation.
‘An intervention to practice a healthy lifestyle earlier in life can protect against cognitive decline or dementia in later life and may also provide other noncognitive benefits.’
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Physical ActivityResearchers reviewed data from 16 trials comparing a physical activity intervention with an inactive control. They found insufficient evidence to conclude the effectiveness of aerobic training, resistance training, or tai chi for improving cognition. The researchers did find low-strength evidence that is combining different types of interventions at the same time, such as physical activity, diet, and cognitive training, improved cognitive test performance.
Prescription Medications
Researchers reviewed data from 51 trials comparing the effect of prescription medication with placebo, usual care, or active control on cognitive outcomes. The evidence did not support use of any of the studied pharmacologic treatments (dementia medications, antihypertensives, diabetes medications, NSAIDs or aspirin, hormones, and lipid-lowering agents) for cognitive protection in persons with normal cognition or mild cognitive impairment.
Cognitive Training
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Over-the-counter Vitamins and Supplements
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According to the researchers, the reasons these interventions fail is not entirely clear. It is possible that they simply do not work to improve cognition, or it could also be that the studies started the interventions too late in life, didn’t use them long enough, or because of shortcomings in many of the studies.
Researchers note that while there was no evidence about whether an intervention to practice a healthy lifestyle earlier in life protects against cognitive decline or dementia in later life, it is unlikely to worsen cognition and may have other, noncognitive benefits.
Source-Eurekalert