New research has shed light on a potential obesity treatment drug that targets the two sides of the appetite, i.e., hunger and feeling full.
Scientists at American Chemical Society (ACS) have designed a hormone-like compound to suppress hunger and boost satiety, or a full feeling, at the same time.
According to their study, Constance Chollet and colleagues targeted two main receptors in the body that help keep appetite in check.
The researchers designed a peptide that binds both the ghrelin and Y2 receptors. They administered it to obese mice and found that those that received the novel peptide ate less than the other mice.
The study is published in ACS' Journal of Medicinal Chemistry.